2,6-Dimethyl-4-(piperidin-1-ylmethyl)phenol

Base Information

• Chemical Name: 2,6-Dimethyl-4-(piperidin-1-ylmethyl)phenol
• CAS No.: 42900-97-0
• Molecular Formula: C14H21NO
• Molecular Weight: 219.327
• DSSTox Substance ID: DTXSID50350128
• Wikidata: Q82125910
• Mol file: 42900-97-0.mol

Synonyms:42900-97-0;2,6-dimethyl-4-(piperidin-1-ylmethyl)phenol;2,6-DIMETHYL-4-(1-PIPERIDINYLMETHYL)PHENOL;CHEMBRDG-BB 5337566;ChemDiv1_023602;Oprea1_741251;Oprea1_865374;SCHEMBL7735651;HMS654A18;DTXSID50350128;MFCD02224567;STK765754;AKOS000568898;CCG-109069;BS-37742;CS-0315983;N-(3,5-dimethyl-4-hydroxybenzyl)piperidine;2,6-DIMETHYL-4-(PIPERIDINOMETHYL)PHENOL;SR-01000463977;SR-01000463977-1

Chemical Property of 2,6-Dimethyl-4-(piperidin-1-ylmethyl)phenol

Chemical Property:

• Vapor Pressure: 9.58E-05mmHg at 25°C
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 219.162314293
• Heavy Atom Count: 16
• Complexity: 201

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC(=C1O)C)CN2CCCCC2

Technology Process of 2,6-Dimethyl-4-(piperidin-1-ylmethyl)phenol

There total 2 articles about 2,6-Dimethyl-4-(piperidin-1-ylmethyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

piperidine (110-89-4) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2.6-dimethylphenol (576-26-1,25134-01-4) → 1-<(4-Hydroxy-3,5-dimethyl-phenyl)-methyl>-piperidin (42900-97-0)

Guidance literature:

With ethanol;

Reference yield:

→ 1-<(4-Hydroxy-3,5-dimethyl-phenyl)-methyl>-piperidin (42900-97-0)

Guidance literature:

aq.aethanol.Formaldehyd 1) aethanol. Piperidin, 0grad 2) 2,6-Dimethyl-phenol/Aethanol, 20grad 1h, Siedetemp. 4h;

Reference yield: 90.0%

5-(4-chlorophenyl)-1H-tetrazole (16687-61-9) + 1-<(4-Hydroxy-3,5-dimethyl-phenyl)-methyl>-piperidin (42900-97-0) → 4-[5-(4-Chloro-phenyl)-tetrazol-1-ylmethyl]-2,6-dimethyl-phenol

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 112 ℃; for 0.3h; Irradiation;

DOI:10.1007/BF00534267

upstream raw materials:

piperidine

formaldehyd

2.6-dimethylphenol

Downstream raw materials:

2,6-dimethyl-4-[(5-phenyl-2H-tetrazol-2-yl)methyl]phenol

2,6-Dimethyl-4-(5-pyridin-3-yl-tetrazol-2-ylmethyl)-phenol

4-(5-Benzyl-tetrazol-1-ylmethyl)-2,6-dimethyl-phenol

4-(5-Benzyl-tetrazol-2-ylmethyl)-2,6-dimethyl-phenol