1-Azabicyclo[2.2.2]octan-3-ol, 3-phenyl-

Base Information

Chemical Name:1-Azabicyclo[2.2.2]octan-3-ol, 3-phenyl-
CAS No.:42925-15-5
Molecular Formula:C13H17NO
Molecular Weight:203.28000
Hs Code.:
Mol file:42925-15-5.mol

Synonyms:3-Phenyl-1-aza-bicyclo[2.2.2]octan-3-ol;3-Phenyl-3-hydroxy-chinuclidin;3-Hydroxy-3-phenyl-chinuclidin;3-Phenyl-chinuclidin-3-ol;

Suppliers and Price of 1-Azabicyclo[2.2.2]octan-3-ol, 3-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Phenylquinuclidin-3-ol 97%
5g
$ 752.00

Total 2 raw suppliers

Chemical Property of 1-Azabicyclo[2.2.2]octan-3-ol, 3-phenyl-

Chemical Property:

Melting Point:165 - 167 °C
PSA：23.47000
LogP:1.53770

Purity/Quality:

97% ^*data from raw suppliers

3-Phenylquinuclidin-3-ol 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-Azabicyclo[2.2.2]octan-3-ol, 3-phenyl-

There total 5 articles about 1-Azabicyclo[2.2.2]octan-3-ol, 3-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1193-65-3
3-quinuclidinone hydrochloride

: 591-51-5
phenyllithium

: 42925-15-5
3-phenyl-quinuclidin-3-ol

Guidance literature:: 3-quinuclidinone hydrochloride; With sodium hydroxide; In water; at 25 ℃; for 2h; Inert atmosphere;

phenyllithium; With lithium chloride; In tetrahydrofuran; at 0 - 25 ℃; for 8h; Inert atmosphere;
DOI:10.1021/jacs.1c05852

Reference yield:

: 3731-38-2
3-Quinuclidinone

: 108-86-1,52753-63-6
bromobenzene

: 42925-15-5
3-phenyl-quinuclidin-3-ol

Guidance literature:: With sec.-butyllithium; Yield given. Multistep reaction; 1.) cyclohexane, THF, -78 deg C, 5 min, 2.) cyclohexane, THF, a) -78 deg 30 min, b) from -78 deg C to RT, 2 h;
DOI:10.1021/jm950907l