2,2,2-Trifluoro-n-(3-hydroxy-4-methoxybenzyl)-n-[2-(4-hydroxyphenyl)ethyl]acetamide

Base Information

Chemical Name:2,2,2-Trifluoro-n-(3-hydroxy-4-methoxybenzyl)-n-[2-(4-hydroxyphenyl)ethyl]acetamide
CAS No.:26668-50-8
Molecular Formula:C18H18 F3 N O4
Molecular Weight:369.335
Hs Code.:
NSC Number:159940
DSSTox Substance ID:DTXSID60303680
Wikidata:Q82049083

Synonyms:2,2,2-trifluoro-n-(3-hydroxy-4-methoxybenzyl)-n-[2-(4-hydroxyphenyl)ethyl]acetamide;26668-50-8;NSC159940;DTXSID60303680;SFKAZNQVZABSAI-UHFFFAOYSA-N;AKOS004907132;NSC-159940

Suppliers and Price of 2,2,2-Trifluoro-n-(3-hydroxy-4-methoxybenzyl)-n-[2-(4-hydroxyphenyl)ethyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2,2,2-Trifluoro-n-(3-hydroxy-4-methoxybenzyl)-n-[2-(4-hydroxyphenyl)ethyl]acetamide

Chemical Property:

Vapor Pressure:2.39E-13mmHg at 25°C
Boiling Point:564.5°C at 760 mmHg
Flash Point:295.2°C
Density:1.347g/cm³
XLogP3:3.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:369.11879254
Heavy Atom Count:26
Complexity:452

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)CN(CCC2=CC=C(C=C2)O)C(=O)C(F)(F)F)O

Technology Process of 2,2,2-Trifluoro-n-(3-hydroxy-4-methoxybenzyl)-n-[2-(4-hydroxyphenyl)ethyl]acetamide

There total 2 articles about 2,2,2-Trifluoro-n-(3-hydroxy-4-methoxybenzyl)-n-[2-(4-hydroxyphenyl)ethyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 4579-60-6
N-(p-hydroxyphenylethyl)-N-(3-hydroxy-4-methoxybenzyl)amine

: 407-25-0
trifluoroacetic anhydride

: 26668-50-8
2,2,2-trifluoro-N-(3-hydroxy-4-methoxybenzyl)-N-(4-hydroxyphenethyl)acetamide

Guidance literature:: With pyridine; at 0 - 20 ℃;
DOI:10.1055/s-0030-1258486

Reference yield:

: 26668-50-8
2,2,2-trifluoro-N-(3-hydroxy-4-methoxybenzyl)-N-(4-hydroxyphenethyl)acetamide

Guidance literature:: O-Methylnorbelladin, Trifluoressigsaeureanhydr.;
DOI:10.1021/ja00707a074

Reference yield: 68.0%

: 26668-50-8
2,2,2-trifluoro-N-(3-hydroxy-4-methoxybenzyl)-N-(4-hydroxyphenethyl)acetamide

: 1254058-60-0
N-(3,4-dihydroxyphenethyl)-2,2,2-trifluoro-N-(3-hydroxy-4-methoxybenzyl)acetamide

Guidance literature:: With oxygen; sodium L-ascorbate; tyrosinase; In acetone; at 20 ℃; for 6h; aq. phosphate buffer; Enzymatic reaction;
DOI:10.1055/s-0030-1258486