3,4-DIMETHYL-6-NITROBENZOIC ACID

Base Information

• Chemical Name: 3,4-DIMETHYL-6-NITROBENZOIC ACID
• CAS No.: 4315-14-4
• Molecular Formula: C9H9NO4
• Molecular Weight: 195.175
• Hs Code.: 2916399090
• Mol file: 4315-14-4.mol

Synonyms:4,5-Dimethyl-2-nitro-benzoesaeure;3,4-Dimethyl-6-nitro-benzoesaeure;3,4-Dimethyl-6-carboxy-nitrobenzol;2-Nitro-4,5-dimethyl-benzoesaeure;Benzoic acid,4,5-dimethyl-2-nitro;

Chemical Property of 3,4-DIMETHYL-6-NITROBENZOIC ACID

Chemical Property:

• PSA: 83.12000
• LogP: 2.43300

Purity/Quality:

98% ^*data from raw suppliers

4,5-Dimethyl-2-nitrobenzoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4,5-Dimethyl-2-nitrobenzoic Acid is a useful reactant for the synthesis of mono-?acylated derivatives containing bergenin and was tested for its potential as an antiglycation.

Technology Process of 3,4-DIMETHYL-6-NITROBENZOIC ACID

There total 6 articles about 3,4-DIMETHYL-6-NITROBENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3,4-dimethylbenzoic acid (619-04-5) → 4,5-Dimethyl-2-nitrobenzoesaeure (4315-14-4) + 2-amino-3,4-dimethylbenzoic acid (50419-58-4) + 3-amino-4,5-dimethylbenzoic acid (348165-23-1)

Guidance literature:

3,4-dimethylbenzoic acid; With nitric acid; at 0 ℃; for 10h;

With hydrogen; palladium on activated charcoal; In methanol; for 10h; under 2844.31 Torr;

DOI:10.1016/S0223-5234(02)01406-X

Reference yield:

3,4-dimethylbenzoic acid (619-04-5) → 4,5-Dimethyl-2-nitrobenzoesaeure (4315-14-4) + 3,4-Dimethyl-2-nitrobenzoesaeure (4315-13-3) + 3,4-Dimethyl-5-nitrobenzoesaeure (74319-96-3)

Guidance literature:

With sulfuric acid; potassium nitrate; at 0 ℃; for 1h;

DOI:10.1002/hlca.19800630208

Reference yield:

2,3-dimethyl-6-nitrobenzonitrile (15089-77-7) → 4,5-Dimethyl-2-nitrobenzoesaeure (4315-14-4)

Guidance literature:

With sulfuric acid;

upstream raw materials:

2,3-dimethyl-6-nitrobenzonitrile

3,4-dimethylbenzoic acid

4,5-dimethyl-2-nitrobenzenamine

N-(3,4-dimethylphenyl)acetamide

Downstream raw materials:

2-amino-4,5-dimethylbenzoic acid

Refernces

• 1、 Courtin, Alfred,Tobel, Hans-Rudolf von. "Zur Synthese sulfonierter Derivate von 2,3-Dimethylanilin und 3,4-Dimethylanilin". . p. 385 - 394. Retrieved 2007/10/02.