3-CHLORO-5-(TRIFLUOROMETHOXY)PHENYLACETIC ACID

Base Information

• Chemical Name: 3-CHLORO-5-(TRIFLUOROMETHOXY)PHENYLACETIC ACID
• CAS No.: 433938-70-6
• Molecular Formula: C9H6ClF3O3
• Molecular Weight: 254.593
• Hs Code.: 2916399090
• Mol file: 433938-70-6.mol

Synonyms:

Chemical Property of 3-CHLORO-5-(TRIFLUOROMETHOXY)PHENYLACETIC ACID

Chemical Property:

• PSA: 46.53000
• LogP: 2.86570

Purity/Quality:

99% ^*data from raw suppliers

3-Chloro-5-(trifluoromethoxy)phenylacetic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-CHLORO-5-(TRIFLUOROMETHOXY)PHENYLACETIC ACID

There total 1 articles about 3-CHLORO-5-(TRIFLUOROMETHOXY)PHENYLACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

3-chloro-5-trifluoromethoxybenzyl cyanide (433938-69-3) → 3-chloro-5-trifluoromethoxyphenylacetic acid (433938-70-6)

Guidance literature:

3-chloro-5-trifluoromethoxybenzyl cyanide; With potassium hydroxide; water; In isopropyl alcohol; at 20 ℃; for 18h; Heating / reflux;

With hydrogenchloride; In water;

Reference yield: 96.0%

3-chloro-5-trifluoromethoxyphenylacetic acid (433938-70-6) + ethanol (64-17-5) → (iv)-Ethyl 3-chloro-5-trifluoromethoxyphenylacetate (433938-71-7)

Guidance literature:

3-chloro-5-trifluoromethoxyphenylacetic acid; ethanol; With sulfuric acid; In ethanol; at 20 ℃; for 18h; Heating / reflux;

With sodium hydrogencarbonate; In ethanol;

upstream raw materials:

3-chloro-5-trifluoromethoxybenzyl cyanide

Downstream raw materials:

(iv)-Ethyl 3-chloro-5-trifluoromethoxyphenylacetate

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