Ethylphosphonic acid methylethyl ester

Base Information

• Chemical Name: Ethylphosphonic acid methylethyl ester
• CAS No.: 5301-65-5
• Molecular Formula: C5H13O3P
• Molecular Weight: 152.13
• Hs Code.: 2931900090
• Mol file: 5301-65-5.mol

Synonyms:Ethyl methyl ethylphosphonate;Phosphonic acid,ethyl-,ethyl methyl ester;(+-)-Ethylphosphonsaeure-methylester-ethylester;Methyl-aethyl-aethylphosphonat;Ethanphosphonsaeuremethylethylester;Methyl-ethyl-ethylphosphonat;

Chemical Property of Ethylphosphonic acid methylethyl ester

Chemical Property:

• Vapor Pressure: 0.975mmHg at 25°C
• Boiling Point: 185°Cat760mmHg
• Flash Point: 80°C
• PSA: 45.34000
• Density: 1.028g/cm³
• LogP: 1.88230

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethylphosphonic acid methylethyl ester

There total 6 articles about Ethylphosphonic acid methylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

ethyl-thiophosphonic acid O-ethyl ester-O'-methyl ester (15720-03-3) → Ethyl methyl ethylphosphonate (5301-65-5)

Guidance literature:

With ozone; In dichloromethane; at -75 ℃;

DOI:10.1055/s-1983-30407

Reference yield:

ethylphosphonic acid diethyl ester (78-38-6) + methyl p-toluene sulfonate (80-48-8) → dimethyl ethylphosphonate (6163-75-3) + Ethyl methyl ethylphosphonate (5301-65-5) + ethyl ester of p-toluenesulfonic acid (80-40-0)

Guidance literature:

at 130 - 140 ℃; for 3.5h;

DOI:10.1021/jo01255a043

Reference yield:

1-cyano-2,2-bis(methoxy)ethylene (15732-02-2) + ethyl hydrogen ethylphosphonate (7305-61-5) → Ethyl methyl ethylphosphonate (5301-65-5)

Guidance literature:

In benzene;

upstream raw materials:

1-cyano-2,2-bis(methoxy)ethylene

ethyl hydrogen ethylphosphonate

ethylphosphonic acid diethyl ester

methyl p-toluene sulfonate

Refernces

• 1、 Skowronska, Aleksandra,Krawczyk, Ewa. "A General Method for the Conversion of Thiophosphoryl and Selenophosphoryl Groups into Phosphoryl Groups by Ozone Oxidation". . p. 509 - 510. Retrieved 2007/10/02.