2,2,3,3-Tetrafluoro-3-(heptafluoropropoxy)propionic acid

Base Information

• Chemical Name: 2,2,3,3-Tetrafluoro-3-(heptafluoropropoxy)propionic acid
• CAS No.: 378-03-0
• Molecular Formula: C6H F11 O3
• Molecular Weight: 330.055
• Hs Code.: 2918990090
• European Community (EC) Number: 206-822-8
• UNII: WW8AR7DXK2
• DSSTox Substance ID: DTXSID20191242
• Nikkaji Number: J213.597C
• Wikidata: Q83063763
• Mol file: 378-03-0.mol

Synonyms:2,2,3,3-Tetrafluoro-3-(heptafluoropropoxy)propionic acid;378-03-0;WW8AR7DXK2;2,2,3,3-tetrafluoro-3-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoic acid;EINECS 206-822-8;UNII-WW8AR7DXK2;CF3CF2CF2OCF2CF2COOH;C6HF11O3;SCHEMBL15792295;DTXSID20191242;MPQDGDVBZJSJIA-UHFFFAOYSA-N;FT-0774643;2,2,3,3-Tetrafluoro-3-(heptafluoropropyloxy)propionic acid;Propanoic acid, 2,2,3,3-tetrafluoro-3-(1,1,2,2,3,3,3-heptafluoropropoxy)-;tetrafluoro-2-(heptafluoropropoxy)propanoic acid, Perfluoro-2-propoxypropanoic acid

Chemical Property of 2,2,3,3-Tetrafluoro-3-(heptafluoropropoxy)propionic acid

Chemical Property:

• Vapor Pressure: 0.847mmHg at 25°C
• Boiling Point: 167.5°Cat760mmHg
• Flash Point: 55.1°C
• PSA: 46.53000
• Density: 1.748g/cm³
• LogP: 3.10610
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 14
• Rotatable Bond Count: 5
• Exact Mass: 329.97500367
• Heavy Atom Count: 20
• Complexity: 384

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(=O)(C(C(OC(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)O

Technology Process of 2,2,3,3-Tetrafluoro-3-(heptafluoropropoxy)propionic acid

There total 4 articles about 2,2,3,3-Tetrafluoro-3-(heptafluoropropoxy)propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

1,1,2-trihydro-5-oxa-perfluoro-1-octene (1152098-94-6) → tetrafluoro-3-(heptafluoro-propoxy)-propionic acid (378-03-0)

Guidance literature:

With potassium permanganate; sulfuric acid; In water; at 60 - 70 ℃; for 3h;

Reference yield:

CF3CF2CF2OCH2CF2COOH (824393-34-2) → CF3CF2CF2OCHFCF2COOH + tetrafluoro-3-(heptafluoro-propoxy)-propionic acid (378-03-0)

Guidance literature:

With fluorine; In nitrogen; at 60 ℃; for 15.3h;

Reference yield:

Perfluoro(3-propoxypropionyl) fluoride (356-61-6) → tetrafluoro-3-(heptafluoro-propoxy)-propionic acid (378-03-0)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

Perfluoro(3-propoxypropionyl) fluoride

CF₃CF₂CF₂OCH₂CF₂COOH

1,1,2-trihydro-5-oxa-perfluoro-1-octene

3-propoxy-propionyl chloride

Refernces

• 1、 -. "Fluoroalkyl carboxylic acid derivative, method for producing fluorine-containing polymer, and aqueous dispersion of fluorine-containing polymer". Page/Page column 14. . Retrieved 2008/06/13.