7-Aminoclonazepam

Base Information

Chemical Name:7-Aminoclonazepam
CAS No.:4959-17-5
Molecular Formula:C15H12ClN3O
Molecular Weight:285.733
Hs Code.:
European Community (EC) Number:690-801-7
UNII:17D6640Q7Y
DSSTox Substance ID:DTXSID90197913
Nikkaji Number:J2.225J
Wikidata:Q27251904
Metabolomics Workbench ID:49557
ChEMBL ID:CHEMBL1273
Mol file:4959-17-5.mol

Synonyms:7-ACLZ;7-aminoclonazepam

Suppliers and Price of 7-Aminoclonazepam

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
7-Aminoclonazepam solution 100?μg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
1 mL
$ 20.90

Sigma-Aldrich
7-Aminoclonazepam solution 100μg/mL in acetonitrile, ampule of 1mL, certified reference material
915-1ml
$ 20.30

Sigma-Aldrich
7-Aminoclonazepam solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
1 mL
$ 83.30

Sigma-Aldrich
7-Aminoclonazepam solution 1.0mg/mL in acetonitrile, ampule of 1mL, certified reference material
916-1ml
$ 80.70

Cayman Chemical
7-Aminoclonazepam (CRM)
1mg
$ 59.00

American Custom Chemicals Corporation
7-AMINO CLONAZEPAM 95.00%
10MG
$ 1686.30

American Custom Chemicals Corporation
7-AMINO CLONAZEPAM 95.00%
1MG
$ 716.10

AK Scientific
7-Aminoclonazepam
1mg
$ 179.00

Total 25 raw suppliers

Chemical Property of 7-Aminoclonazepam

Chemical Property:

Vapor Pressure:4.69E-11mmHg at 25°C
Melting Point:226-228°C
Refractive Index:1.696
Boiling Point:523.5 °C at 760 mmHg
PKA:12.15±0.70(Predicted)
Flash Point:270.4 °C
PSA：67.48000
Density:1.41 g/cm³
LogP:2.86650
Storage Temp.:Controlled Substance, -20?C Freezer
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:285.0668897
Heavy Atom Count:20
Complexity:412

Purity/Quality:

99% ^*data from raw suppliers

7-Aminoclonazepam solution 100?μg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? ^*data from reagent suppliers

Safty Information:

Pictogram(s): F,Xn
Hazard Codes:F,Xn
Statements: 11-20/21/22-36
Safety Statements: 16-36/37-26

MSDS Files:

Useful:

Canonical SMILES:C1C(=O)NC2=C(C=C(C=C2)N)C(=N1)C3=CC=CC=C3Cl
Uses The major metabolite of Clonazepam (C587080).

Technology Process of 7-Aminoclonazepam

There total 9 articles about 7-Aminoclonazepam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 364046-84-4,364046-86-6,1622-61-3
5-(2-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one

: 4959-17-5
7-Aminoclonazepam

Guidance literature:: With hydrogen; acetic acid; palladium on activated charcoal; In methanol; under 2280.15 Torr;
DOI:10.1016/j.bmc.2008.04.059

Reference yield:

: 2011-66-7
2'-chloro-5-nitro-2-aminobenzophenone

: 4959-17-5
7-Aminoclonazepam

Guidance literature:: Multi-step reaction with 4 steps

1: sodium carbonate / dichloromethane / 0.17 h / Cooling with ice

2: sodium azide / dimethyl sulfoxide / 20 °C

3: triphenylphosphine / toluene / 100 °C / Sealed tube

4: iron; acetic acid / 50 °C

With sodium azide; iron; sodium carbonate; acetic acid; triphenylphosphine; In dichloromethane; dimethyl sulfoxide; toluene;

Reference yield:

: 52130-87-7
2-bromo-2'-(2-chlorobenzoyl)-4'-nitroacetanilide

: 4959-17-5
7-Aminoclonazepam

Guidance literature:: Multi-step reaction with 3 steps

1: sodium azide / dimethyl sulfoxide / 20 °C

2: triphenylphosphine / toluene / 100 °C / Sealed tube

3: iron; acetic acid / 50 °C

With sodium azide; iron; acetic acid; triphenylphosphine; In dimethyl sulfoxide; toluene;