1H-Indole, 2-(4-morpholinylmethyl)-

Base Information

Chemical Name:1H-Indole, 2-(4-morpholinylmethyl)-
CAS No.:46739-06-4
Molecular Formula:C13H16N2O
Molecular Weight:216.283
Hs Code.:
DSSTox Substance ID:DTXSID30473788
Nikkaji Number:J2.315.362I
Wikidata:Q82303416
Mol file:46739-06-4.mol

Synonyms:46739-06-4;2-(morpholin-4-ylmethyl)-1H-indole;1H-Indole, 2-(4-morpholinylmethyl)-;DTXSID30473788;2-[(morpholin-4-yl)methyl]-1H-indole;EN300-340000

Suppliers and Price of 1H-Indole, 2-(4-morpholinylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 1H-Indole, 2-(4-morpholinylmethyl)-

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:216.126263138
Heavy Atom Count:16
Complexity:228

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1CC2=CC3=CC=CC=C3N2

Technology Process of 1H-Indole, 2-(4-morpholinylmethyl)-

There total 1 articles about 1H-Indole, 2-(4-morpholinylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 107-21-1
ethylene glycol

: 146354-70-3
3-benzoyl-2-(N-morpholinomethyl)indole

: 94-33-7
C₉H₁₀O₃

: 46739-06-4
4-((1H-indol-2-yl)methyl)morpholine

Guidance literature:: With toluene-4-sulfonic acid; In benzene; for 6h; Heating;
DOI:10.1002/jhet.5570290601

Reference yield:

: 46739-06-4
4-((1H-indol-2-yl)methyl)morpholine

: 1609030-72-9
(E)-N-(2-(2-(morpholinomethyl)-1H-indol-1-yl)ethyl)-3-(3,4,5-trimethoxyphenyl)acrylamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C

1.2: 0 - 20 °C

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C

3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 8 h / 20 °C

With dmap; lithium aluminium tetrahydride; sodium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm5000672