N-(4-Fluorophenyl)-N-hydroxyformamide

Base Information

• Chemical Name: N-(4-Fluorophenyl)-N-hydroxyformamide
• CAS No.: 96018-74-5
• Molecular Formula: C7H6FNO2
• Molecular Weight: 155.1264
• DSSTox Substance ID: DTXSID10242095
• Wikidata: Q83125693
• Mol file: 96018-74-5.mol

Synonyms:N-(4-Fluorophenyl)-N-hydroxyformamide;96018-74-5;NIOSH/LR1020000;N-(p-Fluorophenyl)formohydroxamic acid;Formohydroxamic acid, N-(p-fluorophenyl)-;LR10200000;CCRIS 5137;DTXSID10242095

Chemical Property of N-(4-Fluorophenyl)-N-hydroxyformamide

Chemical Property:

• Vapor Pressure: 0.00124mmHg at 25°C
• Boiling Point: 286.3°Cat760mmHg
• Flash Point: 127°C
• Density: 1.41g/cm³
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 155.03825660
• Heavy Atom Count: 11
• Complexity: 134

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1N(C=O)O)F

Technology Process of N-(4-Fluorophenyl)-N-hydroxyformamide

There total 1 articles about N-(4-Fluorophenyl)-N-hydroxyformamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

4-fluoro-nitrosobenzene (352-15-8) + Glyoxilic acid (298-12-4) → 4-fluoro-N-hydroxy-benzamide (96018-74-5)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 40 ℃; for 2h;

DOI:10.1021/jo01302a017

upstream raw materials:

4-fluoro-nitrosobenzene

Glyoxilic acid