N-(Cyclopropylmethyl)normorphine

Base Information

Chemical Name:N-(Cyclopropylmethyl)normorphine
CAS No.:1976-45-0
Molecular Formula:C₂₀H₂₃NO₃
Molecular Weight:325.408
Hs Code.:
DSSTox Substance ID:DTXSID20173442
Nikkaji Number:J406.898J
Wikidata:Q83043503
Mol file:1976-45-0.mol

Synonyms:N-(cyclopropylmethyl)normorphine

Suppliers and Price of N-(Cyclopropylmethyl)normorphine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of N-(Cyclopropylmethyl)normorphine

Chemical Property:

Vapor Pressure:1.33E-11mmHg at 25°C
Boiling Point:519.1°Cat760mmHg
Flash Point:267.8°C
PSA：52.93000
Density:1.42g/cm³
LogP:1.91620
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:325.16779360
Heavy Atom Count:24
Complexity:575

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC1CN2CCC34C5C2CC6=C3C(=C(C=C6)O)OC4C(C=C5)O
Isomeric SMILES:C1CC1CN2CC[C@]34[C@@H]5[C@H]2CC6=C3C(=C(C=C6)O)O[C@H]4[C@H](C=C5)O

Technology Process of N-(Cyclopropylmethyl)normorphine

There total 14 articles about N-(Cyclopropylmethyl)normorphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 81815-58-9
3-O,N-dicyclopropylcarbonylnormorphine

: 1976-45-0
17-(cyclopropylmethyl)normorphine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 23h; Ambient temperature;
DOI:10.1248/cpb.39.2000

Reference yield:

: 7051-34-5
cyclopropylcarbinyl bromide

: 91265-72-4
3-<(vinyloxy)carbonyl>normorphine hydrobromide

: 1976-45-0
17-(cyclopropylmethyl)normorphine

Guidance literature:: With sodium hydrogencarbonate; In ethanol; at 80 ℃; for 10h;
DOI:10.1021/jm00376a026

Reference yield:

: 466-97-7,13396-02-6,99295-16-6,142864-36-6
normorphine

: 1976-45-0
17-(cyclopropylmethyl)normorphine

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / triethylamine / CHCl₃ / 8 h / Heating

2: 74 percent / LiAlH₄ / tetrahydrofuran / 23 h / Ambient temperature

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; chloroform;
DOI:10.1248/cpb.39.2000