N-(Cyclopropylmethyl)normorphinone

Base Information

Chemical Name:N-(Cyclopropylmethyl)normorphinone
CAS No.:91265-68-8
Molecular Formula:C₂₀H₂₁NO₃
Molecular Weight:323.392
Hs Code.:
DSSTox Substance ID:DTXSID60919866
Wikidata:Q82892455
Mol file:91265-68-8.mol

Synonyms:N-(cyclopropylmethyl)normorphinone;N-(cyclopropylmethyl)normorphinone perchlorate;N-CPMNM

Suppliers and Price of N-(Cyclopropylmethyl)normorphinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-(Cyclopropylmethyl)normorphinone

Chemical Property:

Vapor Pressure:1.26E-11mmHg at 25°C
Boiling Point:524.6°Cat760mmHg
Flash Point:271.1°C
PSA：49.77000
Density:1.42g/cm³
LogP:2.12440
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:323.15214353
Heavy Atom Count:24
Complexity:614

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC1CN2CCC34C5C2CC6=C3C(=C(C=C6)O)OC4C(=O)C=C5
Isomeric SMILES:C1CC1CN2CC[C@]34[C@@H]5[C@H]2CC6=C3C(=C(C=C6)O)O[C@H]4C(=O)C=C5

Technology Process of N-(Cyclopropylmethyl)normorphinone

There total 10 articles about N-(Cyclopropylmethyl)normorphinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 91280-58-9
3-(tert-butyldimethylsilyl)-17-(cyclopropylmethyl)normorphinone

: 91265-68-8
17-(cyclopropylmethyl)normorphinone

Guidance literature:: With hydrogenchloride; at 25 ℃; for 24h;
DOI:10.1021/jm00376a026

Reference yield:

: 1976-45-0
17-(cyclopropylmethyl)normorphine

: 91265-68-8
17-(cyclopropylmethyl)normorphinone

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) n-butyllithium / 1.) DME, hexane, 2.) DME, hexane, 25 deg C, 5 h

2: silver carbonate / benzene / 4 h / Heating

3: 1 N aq. HCl / 24 h / 25 °C

With hydrogenchloride; n-butyllithium; silver carbonate; In benzene;
DOI:10.1021/jm00376a026

Reference yield:

: 91265-74-6
3-(tert-butyldimethylsilyl)-17-(cyclopropylmethyl)normorphine

: 91265-68-8
17-(cyclopropylmethyl)normorphinone

Guidance literature:: Multi-step reaction with 2 steps

1: silver carbonate / benzene / 4 h / Heating

2: 1 N aq. HCl / 24 h / 25 °C

With hydrogenchloride; silver carbonate; In benzene;
DOI:10.1021/jm00376a026