Acetyl-leucyl-leucyl-argininal

Base Information

Chemical Name:Acetyl-leucyl-leucyl-argininal
CAS No.:24365-47-7
Molecular Formula:C₂₀H₃₈N₆O₄
Molecular Weight:426.56
Hs Code.:
European Community (EC) Number:640-991-2
DSSTox Substance ID:DTXSID20860320
Metabolomics Workbench ID:98810
ChEMBL ID:CHEMBL429947

Synonyms:Leupeptin Ac-LL;Acetyl-leucyl-leucyl-argininal;acetyl-leucyl-leucyl-arginal;24365-47-7;CHEMBL429947;SCHEMBL11021602;DTXSID20860320;Bio1_000402;Bio1_000891;Bio1_001380;NCGC00389796-01;NCI60_004807;N-acetylleucyl-N-{5-[(diaminomethylidene)amino]-1-oxopentan-2-yl}leucinamide

Suppliers and Price of Acetyl-leucyl-leucyl-argininal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 15 raw suppliers

Chemical Property of Acetyl-leucyl-leucyl-argininal

Chemical Property:

Refractive Index:1.557
Boiling Point:°Cat760mmHg
PKA:13.44±0.46(Predicted)
Flash Point:°C
PSA：166.27000
Density:1.21g/cm³
LogP:2.37870
XLogP3:0.4
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:14
Exact Mass:426.29545371
Heavy Atom Count:30
Complexity:602

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C=O)NC(=O)C

Technology Process of Acetyl-leucyl-leucyl-argininal

There total 14 articles about Acetyl-leucyl-leucyl-argininal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 45314-99-6,120852-58-6
Ac-L--Leu-L-Leu-L-Argal dibutylacetal

: 24365-47-7,55123-66-5,59492-10-3
leupeptin

Guidance literature:: With hydrogenchloride; In acetonitrile; at 37 ℃; for 2h; Yield given;
DOI:10.1248/cpb.30.2319

Reference yield:

: 2018-66-8
Z-Leu-OH

: 24365-47-7,55123-66-5,59492-10-3
leupeptin

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) HOSu, DCCD 2.) triethylamine / 1.) chloroform, 0 deg C, 4 h 2.) chloroform, DMF, 2 d, room temp.

2: hydrogen / palladium / methanol / 4.5 h

3: triethylamine / dimethylformamide; H₂O / 72 h / Ambient temperature; pH=8.0

4: 1N HCl / acetonitrile / 2 h / 37 °C

With hydrogenchloride; 1-hydroxy-pyrrolidine-2,5-dione; hydrogen; triethylamine; dicyclohexyl-carbodiimide; palladium; In methanol; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1248/cpb.30.2319

Reference yield:

: 2018-66-8
Z-Leu-OH

: 24365-47-7
leupeptin

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) HOSu, DCCD 2.) triethylamine / 1.) chloroform, 0 deg C, 4 h 2.) chloroform, DMF, 2 d, room temp.

2: hydrogen / palladium / methanol / 4.5 h

3: triethylamine / dimethylformamide; H₂O / 72 h / Ambient temperature; pH=8.0

4: 1N HCl / acetonitrile / 2 h / 37 °C

5: 0.1 m aq. sodium carbonate / 20 h / 37 °C

With hydrogenchloride; 1-hydroxy-pyrrolidine-2,5-dione; hydrogen; sodium carbonate; triethylamine; dicyclohexyl-carbodiimide; palladium; In methanol; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1248/cpb.30.2319