3-(5-methyl-1,3-benzoxazol-2-yl)aniline

Base Information

• Chemical Name: 3-(5-methyl-1,3-benzoxazol-2-yl)aniline
• CAS No.: 7509-65-1
• Molecular Formula: C14H12N2O
• Molecular Weight: 224.262
• Mol file: 7509-65-1.mol

Synonyms:3-(5-methylbenzoxazol-2-yl)phenylamine;3-(5-Methyl-benzooxazol-2-yl)-phenylamine;3-(5-methyl-benzoxazol-2-yl)-aniline;

Chemical Property of 3-(5-methyl-1,3-benzoxazol-2-yl)aniline

Chemical Property:

• Vapor Pressure: 2.79E-06mmHg at 25°C
• Boiling Point: 389.7°Cat760mmHg
• Flash Point: 189.5°C
• PSA: 52.05000
• Density: 1.222g/cm³
• LogP: 3.96660

Purity/Quality:

3-(5-methylbenzo[d]oxazol-2-yl)aniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(5-methyl-1,3-benzoxazol-2-yl)aniline

There total 9 articles about 3-(5-methyl-1,3-benzoxazol-2-yl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

5-methyl-2-(3-nitro-phenyl)-benzooxazole (25284-11-1) → 3-(5-methylbenzo[d]oxazol-2-yl)aniline (7509-65-1)

Guidance literature:

5-methyl-2-(3-nitro-phenyl)-benzooxazole; With hydrogen; acetic acid; palladium 10% on activated carbon; at 20 ℃; for 4h; under 3040.2 Torr;

With sodium hydrogencarbonate; In water; ethyl acetate;

Reference yield: 83.0%

→ 3-(5-methylbenzo[d]oxazol-2-yl)aniline (7509-65-1)

Guidance literature:

Reference yield: 71.0%

meta-aminobenzoic acid (99-05-8,159139-79-4) + 3-amino-4-hydroxytoluene (95-84-1) → 3-(5-methylbenzo[d]oxazol-2-yl)aniline (7509-65-1)

Guidance literature:

With PPA; at 185 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.ejmech.2017.12.088

upstream raw materials:

5-methyl-2-(3-nitro-phenyl)-benzooxazole

m-nitrobenzoic acid chloride

3-nitrobenzoic acid

N-(2-hydroxy-5-methyl-phenyl)-3-nitro-benzamide