5-Methyl-2-(3-nitrophenyl)-1,3-benzoxazole

Base Information

Chemical Name:5-Methyl-2-(3-nitrophenyl)-1,3-benzoxazole
CAS No.:25284-11-1
Molecular Formula:C₁₄H₁₀N₂O₃
Molecular Weight:254.245
Hs Code.:
DSSTox Substance ID:DTXSID201287279
Nikkaji Number:J2.562.494G

Synonyms:5-methyl-2-(3-nitrophenyl)-1,3-benzoxazole;5-methyl-2-(3-nitrophenyl)benzoxazole;Oprea1_696173;SCHEMBL4508204;DTXSID201287279;STK038867;AKOS000642717;2-(3-Nitrophenyl)-5-methylbenzoxazole;25284-11-1;2-{3-nitrophenyl}-5-methyl-1,3-benzoxazole;AG-690/11836033

Suppliers and Price of 5-Methyl-2-(3-nitrophenyl)-1,3-benzoxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-Methyl-2-(3-nitrophenyl)-1,3-benzoxazole

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:254.06914219
Heavy Atom Count:19
Complexity:344

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)OC(=N2)C3=CC(=CC=C3)[N+](=O)[O-]

Technology Process of 5-Methyl-2-(3-nitrophenyl)-1,3-benzoxazole

There total 6 articles about 5-Methyl-2-(3-nitrophenyl)-1,3-benzoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 95-84-1
3-amino-4-hydroxytoluene

: 121-90-4
m-nitrobenzoic acid chloride

: 25284-11-1
5-methyl-2-(3-nitro-phenyl)-benzooxazole

Guidance literature:: 3-amino-4-hydroxytoluene; m-nitrobenzoic acid chloride; In 1,4-dioxane; at 210 ℃; for 0.25h; Microwave irradiation;

With sodium hydroxide; In 1,4-dioxane; water;

Reference yield: 79.0%

: 95-84-1
3-amino-4-hydroxytoluene

: 121-92-6
3-nitrobenzoic acid

: 25284-11-1
5-methyl-2-(3-nitro-phenyl)-benzooxazole

Guidance literature:: 3-nitrobenzoic acid; With trichloroisocyanuric acid; triphenylphosphine; In 1,4-dioxane; at 20 ℃; for 0.5h; Inert atmosphere; Sealed tube; Microwave irradiation;

3-amino-4-hydroxytoluene; In 1,4-dioxane; at 180 ℃; for 0.416667h; Inert atmosphere; Sealed tube; Microwave irradiation;
DOI:10.1016/j.bmcl.2019.05.021