BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE

Base Information

• Chemical Name: BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE
• CAS No.: 187393-00-6
• Molecular Formula: C38H49N3O5
• Molecular Weight: 627.824
• Hs Code.: 2933690000
• Mol file: 187393-00-6.mol

Synonyms:2,2'-(6-(4-Methoxyphenyl)-1,3,5-triazine-2,4-diyl)bis(5-((2-ethylhexyl)oxy)phenol);Bis-ethylhexyloxyphenol methoxyphenyl triazine;UNII-PWZ1720CBH;Tinosorb S;BEMT;

Chemical Property of BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE

Chemical Property:

• Vapor Pressure: 1.37E-13mmHg at 25°C
• Melting Point: 83-85°; mp 80° (Mongiat)
• Boiling Point: 781.977 °C at 760 mmHg
• PKA: 8.08±0.40(Predicted)
• Flash Point: 426.724 °C
• PSA: 106.82000
• Density: 1.11 g/cm³
• LogP: 9.48280
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Ethyl Acetate (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

Bemotrizinol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Bemotrizinol, or bis-ethylhexyloxyphenol methoxyphenyl triazine, is an organic UV filter found in over-the-counter sunscreen products. It primarily absorbs UV-A rays. Compared to older broad-spectrum chemical agents, bemotrizinol is more more fat soluble (oil soluble in cosmetic oils) to aid in efficacy and broad-spectrum activity. It is claimed to be photostable, which increases its onset of action and its efficiency in providing protection against UV-rays upon topical application. Bemotrizinol is commonly marketed as Tinosorb S and Escalol S.
• Uses: Bemotrizinol is a broad-spectrum UV absorber, absorbing both UVA and UVB. Bemotrizinol is added to various sunscreens to absorb UV rays.

Technology Process of BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE

There total 8 articles about BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.9%

2,4-dichloro-6-(4-methoxy-phenyl)-[1,3,5]triazine (90723-86-7) + 3-ethylhexyloxyphenol → tinosorb S (187393-00-6)

Guidance literature:

2,4-dichloro-6-(4-methoxy-phenyl)-[1,3,5]triazine; 3-ethylhexyloxyphenol; With aluminum (III) chloride; In chlorobenzene; at 40 - 60 ℃;

In water; at 40 - 60 ℃;

Reference yield:

2,4-dichloro-6-(4-methoxy-phenyl)-[1,3,5]triazine (90723-86-7) + recorcinol (108-46-3) → tinosorb S (187393-00-6) + 4-[4-(2,4-dihydroxyphenyl)-6-(4-methoxyphenyl)-1,3,5-triazin-2-yl]benzene-1,3-diol (1440-00-2)

Guidance literature:

aluminium chloride; In sulfolane; methanol; 5,5-dimethyl-1,3-cyclohexadiene;

Reference yield:

3-bromomethylheptane (18908-66-2) + 4-[4-(2,4-dihydroxyphenyl)-6-(4-methoxyphenyl)-1,3,5-triazin-2-yl]benzene-1,3-diol (1440-00-2) → tinosorb S (187393-00-6)

Guidance literature:

With sodium carbonate; In N,N-dimethyl-formamide; at 125 ℃;

upstream raw materials:

2,4-dichloro-6-(4-methoxy-phenyl)-[1,3,5]triazine

recorcinol

3-(chloromethyl)heptane

4-[4-(2,4-dihydroxyphenyl)-6-(4-methoxyphenyl)-1,3,5-triazin-2-yl]benzene-1,3-diol

Refernces

• 1、 -. "Etherification synthesis method of ultraviolet light absorberTinosorb S". Paragraph 0032; 0037-0044; 0049-0051; 0056-0058; 0063; .... . Retrieved 2021/07/24.
• 2、 -. "Manufacturing method of triazine-based compound and derivative thereof". Paragraph 0212-0214. . Retrieved 2020/03/17.