(3R)-3-(4-fluorophenyl)cyclohexan-1-one

Base Information

Chemical Name:(3R)-3-(4-fluorophenyl)cyclohexan-1-one
CAS No.:479586-34-0
Molecular Formula:C12H13FO
Molecular Weight:192.233
Hs Code.:
DSSTox Substance ID:DTXSID40461212
Nikkaji Number:J1.772.169K
Wikidata:Q82285485

Synonyms:CTK1C7037;479586-34-0;SCHEMBL18980759;DTXSID40461212

Suppliers and Price of (3R)-3-(4-fluorophenyl)cyclohexan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (3R)-3-(4-fluorophenyl)cyclohexan-1-one

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:192.095043196
Heavy Atom Count:14
Complexity:206

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(CC(=O)C1)C2=CC=C(C=C2)F
Isomeric SMILES:C1C[C@H](CC(=O)C1)C2=CC=C(C=C2)F

Technology Process of (3R)-3-(4-fluorophenyl)cyclohexan-1-one

There total 8 articles about (3R)-3-(4-fluorophenyl)cyclohexan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 930-68-7
cyclohexenone

: 1765-93-1
4-fluoroboronic acid

: 479586-34-0
(R)-3-(4-fluorophenyl)cyclohexanone

Guidance literature:: With chlorobis(ethylene)rhodium(I) dimer; (R_S,S_C,R_S)-N -[1-(phenylsulfinyl)-3-methylbut-2-yl]-2-methyl-2-propanesulfinamide; potassium hydroxide; In water; toluene; at 20 ℃; for 18h; Reagent/catalyst; enantioselective reaction; Inert atmosphere;
DOI:10.1021/acs.orglett.9b02405

Reference yield: 100.0%

: 479586-34-0
(R)-3-(4-fluorophenyl)cyclohexanone

Guidance literature:: With di-μ-chlorotetrakis(η2-ethylene)dirhodium(I); potassium hydroxide; In ethanol; at 30 ℃; for 1h; enantioselective reaction;

Reference yield: 95.0%

: 930-68-7
cyclohexenone

: potassim 4-fluorophenyltrifluoroborate

: 479586-34-0
(R)-3-(4-fluorophenyl)cyclohexanone

Guidance literature:: [Rh(cyclooctadiene)2](PF₆); (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; In water; toluene; for 2h; Heating;
DOI:10.1016/S0040-4039(02)01288-1