2-Bromo-4-chloro-4'-fluorobutyrophenone

Base Information

Chemical Name:2-Bromo-4-chloro-4'-fluorobutyrophenone
CAS No.:51037-74-2
Molecular Formula:C10H9 Br Cl F O
Molecular Weight:279.536
Hs Code.:2914700090
European Community (EC) Number:256-932-5
DSSTox Substance ID:DTXSID80965325
Nikkaji Number:J261.619J
Mol file:51037-74-2.mol

Synonyms:51037-74-2;2-Bromo-4-chloro-4'-fluorobutyrophenone;EINECS 256-932-5;2-bromo-4-chloro-1-(4-fluorophenyl)butan-1-one;C10H9BrClFO;C10-H9-Br-Cl-F-O;SCHEMBL9211326;DTXSID80965325;LTDBFRKGDVLQLR-UHFFFAOYSA-N;1-p-fluorobenzoyl-1-bromo-3-chloropropane;1-p-fluorobenzoyl-1-bromo-3-chloro-propane;2-Bromo-4-chloro-1-(4-fluorophenyl)-1-butanone

Suppliers and Price of 2-Bromo-4-chloro-4'-fluorobutyrophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-Bromo-4-chloro-4'-fluorobutyrophenone

Chemical Property:

Boiling Point:330.8°Cat760mmHg
Flash Point:153.8°C
PSA：17.07000
Density:1.526g/cm³
LogP:3.40080
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:277.95093
Heavy Atom Count:14
Complexity:193

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)C(CCCl)Br)F

Technology Process of 2-Bromo-4-chloro-4'-fluorobutyrophenone

There total 1 articles about 2-Bromo-4-chloro-4'-fluorobutyrophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 3874-54-2,41167-07-1
4-(4-fluorophenyl)-4-oxo-n-butyl chloride

: 51037-74-2
1-p-fluorobenzoyl-1-bromo-3-chloro-propane

Guidance literature:: With bromine; calcium carbonate; In chloroform; for 8h; Ambient temperature;

Reference yield: 62.0%

: 51037-74-2
1-p-fluorobenzoyl-1-bromo-3-chloro-propane

: 104197-13-9
4-bromo-2,6-difluorophenol

: [1-(4-bromo-2,6-difluorophenoxy)cyclopropyl](4-fluorophenyl)methanone

Guidance literature:: With potassium carbonate; In acetonitrile; for 20h; Inert atmosphere; Reflux;

Reference yield:

: 51037-74-2
1-p-fluorobenzoyl-1-bromo-3-chloro-propane

: 51037-47-9
1-(4-fluorophenyl)-2-hydroxy-4-(4-phenyl-1-piperazinyl)-1-butanone

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / methanol / 24 h / Ambient temperature

2: potassium iodide / toluene / 20 h / Heating

With potassium iodide; In methanol; toluene;