4'-Fluoro-2-hydroxy-4-(4-phenylpiperazin-1-yl)butyrophenone

Base Information

Chemical Name:4'-Fluoro-2-hydroxy-4-(4-phenylpiperazin-1-yl)butyrophenone
CAS No.:51037-47-9
Molecular Formula:C20H23 F N2 O2
Molecular Weight:342.413
Hs Code.:
European Community (EC) Number:256-929-9
DSSTox Substance ID:DTXSID50965317
Nikkaji Number:J67.461C
ChEMBL ID:CHEMBL1190941
Mol file:51037-47-9.mol

Synonyms:51037-47-9;4'-Fluoro-2-hydroxy-4-(4-phenylpiperazin-1-yl)butyrophenone;EINECS 256-929-9;BRN 0843253;4'-Fluoro-2-hydroxy-4-(4-phenyl-1-piperazinyl)butyrophenone;1-(4-Fluorophenyl)-2-hydroxy-4-(4-phenyl-1-piperazinyl)-1-butanone;BUTYROPHENONE, 4'-FLUORO-2-HYDROXY-4-(4-PHENYL-1-PIPERAZINYL)-;1-(4-fluorophenyl)-2-hydroxy-4-(4-phenylpiperazin-1-yl)butan-1-one;CHEMBL1190941;SCHEMBL11831658;DTXSID50965317;LS-48373;4'-Fluoro-alpha-hydroxy-gamma-(4-phenyl-1-piperazinyl)butyrophenone

Suppliers and Price of 4'-Fluoro-2-hydroxy-4-(4-phenylpiperazin-1-yl)butyrophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 4'-Fluoro-2-hydroxy-4-(4-phenylpiperazin-1-yl)butyrophenone

Chemical Property:

Boiling Point:524.1°Cat760mmHg
Flash Point:270.8°C
Density:1.202g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:342.17435614
Heavy Atom Count:25
Complexity:412

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCC(C(=O)C2=CC=C(C=C2)F)O)C3=CC=CC=C3

Technology Process of 4'-Fluoro-2-hydroxy-4-(4-phenylpiperazin-1-yl)butyrophenone

There total 4 articles about 4'-Fluoro-2-hydroxy-4-(4-phenylpiperazin-1-yl)butyrophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51037-74-2
1-p-fluorobenzoyl-1-bromo-3-chloro-propane

: 51037-47-9
1-(4-fluorophenyl)-2-hydroxy-4-(4-phenyl-1-piperazinyl)-1-butanone

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / methanol / 24 h / Ambient temperature

2: potassium iodide / toluene / 20 h / Heating

With potassium iodide; In methanol; toluene;

Reference yield:

: 3874-54-2,41167-07-1
4-(4-fluorophenyl)-4-oxo-n-butyl chloride

: 51037-47-9
1-(4-fluorophenyl)-2-hydroxy-4-(4-phenyl-1-piperazinyl)-1-butanone

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / bromine, CaCO₃ / CHCl₃ / 8 h / Ambient temperature

2: 81 percent / methanol / 24 h / Ambient temperature

3: potassium iodide / toluene / 20 h / Heating

With bromine; calcium carbonate; potassium iodide; In methanol; chloroform; toluene;