Benzene, 1-(bromomethyl)-3,5-diiodo-

Base Information

• Chemical Name: Benzene, 1-(bromomethyl)-3,5-diiodo-
• CAS No.: 49617-78-9
• Molecular Formula: C7H5BrI2
• Molecular Weight: 422.83
• Mol file: 49617-78-9.mol

Synonyms:

Chemical Property of Benzene, 1-(bromomethyl)-3,5-diiodo-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzene, 1-(bromomethyl)-3,5-diiodo-

There total 5 articles about Benzene, 1-(bromomethyl)-3,5-diiodo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-diiodo-5-methylbenzene (49617-79-0) → 1-(bromomethyl)-3,5-diiodobenzene (49617-78-9)

Guidance literature:

With N-Bromosuccinimide; Perbenzoic acid; In 1,2-dichloro-ethane; for 6h; Heating;

DOI:10.1039/jm9960601745

Reference yield:

2,6-diiodo-4-methylaniline (64662-57-3) → 1-(bromomethyl)-3,5-diiodobenzene (49617-78-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 50 percent / aq. NaNO₂, H₂SO₄, ethanol / benzene / 24 h / Heating

2: NBS, benzoyl peroxide / 1,2-dichloro-ethane / 6 h / Heating

With N-Bromosuccinimide; Perbenzoic acid; ethanol; sulfuric acid; sodium nitrite; In 1,2-dichloro-ethane; benzene;

DOI:10.1039/jm9960601745

Reference yield:

p-toluidine (106-49-0,12221-03-3) → 1-(bromomethyl)-3,5-diiodobenzene (49617-78-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 78 percent / benzyltrimethylammonium dichloroiodate, CaCO₃ / CH₂Cl₂; methanol / 24 h / Heating

2: 50 percent / aq. NaNO₂, H₂SO₄, ethanol / benzene / 24 h / Heating

3: NBS, benzoyl peroxide / 1,2-dichloro-ethane / 6 h / Heating

With N-Bromosuccinimide; Perbenzoic acid; ethanol; sulfuric acid; N,N,N-trimethylbenzenemethanaminium dichloroiodate; calcium carbonate; sodium nitrite; In methanol; dichloromethane; 1,2-dichloro-ethane; benzene;

DOI:10.1039/jm9960601745

upstream raw materials:

1,3-diiodo-5-methylbenzene

2,6-diiodo-4-methylaniline

p-toluidine

Downstream raw materials:

N-(3,5-diiodobenzyl)-2-[1,3-dimethylindol-2-ylmethylidene]-3-isopropylidenesuccinimide

N-(3,5-diiodobenzyl)phthalimide

2-(3,5-Diiodo-phenyl)-4,4,5,5-tetramethyl-imidazolidine-1,3-diol