6,8-Dichlorochromanone

Base Information

Chemical Name:6,8-Dichlorochromanone
CAS No.:49660-60-8
Molecular Formula:C9H6Cl2O2
Molecular Weight:217.04900
Hs Code.:
DSSTox Substance ID:DTXSID60594354
Wikidata:Q82489164
Mol file:49660-60-8.mol

Synonyms:6,8-DICHLOROCHROMANONE;916792-25-1;6,8-dichloro-3,4-dihydrochromen-2-one;6,8-dichlorochroman-2-one;6,8-dichloro-chroman-2-one;SCHEMBL6580732;DTXSID60594354;DB-306931;6,8-Dichloro-3,4-dihydro-2H-1-benzopyran-2-one;(S)-3-HYDROXY-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRICACID

Suppliers and Price of 6,8-Dichlorochromanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6,8-dichloro-3,4-dihydro-2H-1-benzopyran-4-one
50mg
$ 90.00

TRC
6,8-dichloro-3,4-dihydro-2H-1-benzopyran-4-one
25mg
$ 45.00

Crysdot
6,8-Dichlorochroman-4-one 97%
1g
$ 887.00

Chemenu
6,8-Dichlorochroman-4-one 97%
1g
$ 837.00

American Custom Chemicals Corporation
6,8-DICHLORO-2,3-DIHYDRO-4H-CHROMEN-4-ONE 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
6,8-DICHLORO-2,3-DIHYDRO-4H-CHROMEN-4-ONE 95.00%
2.5G
$ 1227.82

American Custom Chemicals Corporation
6,8-DICHLORO-2,3-DIHYDRO-4H-CHROMEN-4-ONE 95.00%
1G
$ 852.55

Total 6 raw suppliers

Chemical Property of 6,8-Dichlorochromanone

Chemical Property:

Melting Point:85-86 °C(Solv: ligroine (8032-32-4))
Boiling Point:361.6±42.0 °C(Predicted)
PSA：26.30000
Density:1.469±0.06 g/cm3(Predicted)
LogP:2.84500
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:215.9744848
Heavy Atom Count:13
Complexity:220

Purity/Quality:

95% ^*data from raw suppliers

6,8-dichloro-3,4-dihydro-2H-1-benzopyran-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)OC2=C1C=C(C=C2Cl)Cl

Technology Process of 6,8-Dichlorochromanone

There total 3 articles about 6,8-Dichlorochromanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3284-80-8
3-(2,4-dichlorophenoxy)propionic acid

: 49660-60-8
6,8-dichloro-2,3-dihydrochromen-4-one

Guidance literature:: With sulfuric acid;

Reference yield:

: 3284-80-8
3-(2,4-dichlorophenoxy)propionic acid

: 49660-60-8
6,8-dichloro-2,3-dihydrochromen-4-one

: 63472-21-9
3-([1,1'-biphenyl]-4-yloxy)propanoic acid

Guidance literature:: With phosphorus pentaoxide; In methanesulfonic acid;

Reference yield:

: 120-83-2,40477-79-0
2,4-dichlorophenol

: 49660-60-8
6,8-dichloro-2,3-dihydrochromen-4-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / water / 100 °C

2.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 1.5 h

2.2: 20 °C / Cooling with ice

With oxalyl dichloride; N,N-dimethyl-formamide; sodium hydroxide; In dichloromethane; water;