2-Piperidin-1-ylmethyl-acrylic acid

Base Information

• Chemical Name: 2-Piperidin-1-ylmethyl-acrylic acid
• CAS No.: 4969-03-3
• Molecular Formula: C9H15NO2
• Molecular Weight: 169.22100
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID60435233
• Nikkaji Number: J638.149I
• Mol file: 4969-03-3.mol

Synonyms:2-PIPERIDIN-1-YLMETHYL-ACRYLIC ACID;4969-03-3;2-(Piperidin-1-ylmethyl)acrylic acid;2-[(Piperidin-1-yl)methyl]acrylic acid;2-(piperidin-1-ylmethyl)prop-2-enoic acid;2-[(Piperidin-1-yl)methyl]prop-2-enoic acid;SCHEMBL13719453;DTXSID60435233;2-(Piperidin-1-ylmethyl)acrylicacid;2-Piperidin-1-ylmethyl acrylic acid;AB1575;MFCD06208437;AKOS013434008;SB37355;CS-0340796;EN300-2502476

Chemical Property of 2-Piperidin-1-ylmethyl-acrylic acid

Chemical Property:

• PSA: 40.54000
• LogP: 1.05100
• XLogP3: -1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 169.110278721
• Heavy Atom Count: 12
• Complexity: 183

Purity/Quality:

99% ^*data from raw suppliers

2-Piperidin-1-ylmethyl-acrylicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C=C(CN1CCCCC1)C(=O)O

Technology Process of 2-Piperidin-1-ylmethyl-acrylic acid

There total 2 articles about 2-Piperidin-1-ylmethyl-acrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

piperidine (110-89-4) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + malonic acid (141-82-2) → 2-(1-Piperidino)methacrylsaeure (4969-03-3)

Guidance literature:

In 1,4-dioxane; at 70 ℃; for 1h;

DOI:10.1080/00397919508011401

Reference yield:

→ 2-(1-Piperidino)methacrylsaeure (4969-03-3)

Guidance literature:

Bis-(piperidino)-methan, Malonsaeure;

upstream raw materials:

piperidine

formaldehyd

malonic acid

Refernces