Triphenyl(propyl)phosphonium iodide

Base Information

• Chemical Name: Triphenyl(propyl)phosphonium iodide
• CAS No.: 14350-50-6
• Molecular Formula: C21H22IP
• Molecular Weight: 432.284
• Hs Code.: 2931900090
• NSC Number: 122261
• DSSTox Substance ID: DTXSID40450681
• ChEMBL ID: CHEMBL4163764
• Mol file: 14350-50-6.mol

Synonyms:triphenyl(propyl)phosphonium iodide;14350-50-6;propyltriphenylphosphonium iodide;triphenyl(propyl)phosphanium;iodide;SCHEMBL297568;CHEMBL4163764;triphenyl(propyl)phosphoniumiodide;DTXSID40450681;MPNQDJZRGAOBPW-UHFFFAOYSA-M;triphenyl(propyl)phosphanium iodide;MFCD00050238;n-propyl-triphenyl phosphonium iodide;AKOS015915195;NSC-122261;FT-0658512;A808078

Chemical Property of Triphenyl(propyl)phosphonium iodide

Chemical Property:

• Melting Point: 204 °C(Solv: water (7732-18-5))
• PSA: 13.59000
• LogP: 1.39450
• Storage Temp.: Sealed in dry,Room Temperature
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 432.05039
• Heavy Atom Count: 23
• Complexity: 260

Purity/Quality:

99%, ^*data from raw suppliers

Triphenyl(propyl)phosphonium iodide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[I-]

Technology Process of Triphenyl(propyl)phosphonium iodide

There total 6 articles about Triphenyl(propyl)phosphonium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1-iodo-propane (107-08-4) + triphenylphosphine (603-35-0) → propyl(triphenyl)phosphonium iodide (14350-50-6)

Guidance literature:

In benzene; for 24h; Heating;

DOI:10.1071/C96180

Reference yield: 90.0%

2-(triphenyl-λ5-phosphanylidene)-butyric acid methyl ester (24448-83-7) → propyl(triphenyl)phosphonium iodide (14350-50-6)

Guidance literature:

With sodium iodide; In acetic acid; for 2h; Heating;

DOI:10.1055/s-1981-29497

Reference yield: 74.0%

propyl bromide (106-94-5) + triphenylphosphine (603-35-0) → propyl(triphenyl)phosphonium iodide (14350-50-6)

Guidance literature:

With potassium iodide; In acetonitrile; at 85 ℃;

DOI:10.1021/acsmedchemlett.7b00287

upstream raw materials:

1-iodo-propane

triphenylphosphine

2-(triphenyl-λ⁵-phosphanylidene)-butyric acid methyl ester

chlorobenzene

Downstream raw materials:

diphenylphosphinopropane

(Z)-but-1-en-1-ylbenzene

trans-1-phenyl-1-butene

(2,4-dimethoxyphenyl)butene

Refernces

• 1、 Kiddle, James J.. "Microwave irradiation in organophosphorus chemistry. Part 2: Synthesis of phosphonium salts". . p. 1339 - 1341. Retrieved 2000.
• 2、 Ringstrand, Bryan,Oltmanns, Martin,Batt, Jeffrey A.,Jankowiak, Aleksandra,Denicola, Richard P.,Kaszynski, Piotr. "The preparation of 3-substituted-1,5-dibromo-pentanes as precursors to heteracyclohexanes". supporting information; experimental part. p. 386 - 393. Retrieved 2011/06/23.