1-Iodopropane

Base Information

• Chemical Name: 1-Iodopropane
• CAS No.: 107-08-4
• Molecular Formula: C3H7I
• Molecular Weight: 169.993
• Hs Code.: 29033080
• European Community (EC) Number: 203-460-2
• UN Number: 2392
• UNII: ND3629KE2K
• DSSTox Substance ID: DTXSID501015653
• Nikkaji Number: J4.051G
• Wikipedia: N-Propyl_iodide
• Wikidata: Q161640
• Mol file: 107-08-4.mol

Synonyms:1-iodo-propane;1-iodopropane;propyl iodide

Chemical Property of 1-Iodopropane

Chemical Property:

• Appearance/Colour: colorless transparent liquid
• Vapor Pressure: 38.2mmHg at 25°C
• Melting Point: -101 °C
• Refractive Index: n20/D 1.504(lit.)
• Boiling Point: 102.9 °C at 760 mmHg
• Flash Point: 44.4 °C
• PSA: 0.00000
• Density: 1.754 g/cm³
• LogP: 1.83140
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 169.95925
• Heavy Atom Count: 4
• Complexity: 7.2
• Transport DOT Label: Flammable Liquid

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn:Harmful
• Statements: R10:; R20:; R36/37/38:
• Safety Statements: S16:; S26:; S36/37:

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Halogenated Aliphatics, Saturated
• Canonical SMILES: CCCI

Technology Process of 1-Iodopropane

There total 54 articles about 1-Iodopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

triphenylpropylplumbane (74086-81-0) → iodobenzene (591-50-4) + 1-iodo-propane (107-08-4) + lead(II) iodide (10101-63-0)

Guidance literature:

With I₂; In chloroform-d1; (N2), stirred, treated with 3 equiv I2 at 0°C; filtered; NMR, iodobenzene : 1-iodopropane = 3:1;

DOI:10.1021/om00054a069

Reference yield: 90.0%

2,7-Di-tert-butyl-10b,10c-dipropyl-10b,10c-dihydro-pyrene (76626-77-2) → 2,7-di-tertbutylpyrene (24300-91-2) + 1-iodo-propane (107-08-4)

Guidance literature:

With iodine; In benzene; for 48h; Heating;

DOI:10.1021/ja00377a027

Reference yield: 81.0%

propan-1-ol (71-23-8) → 1-iodo-propane (107-08-4)

Guidance literature:

With iodine; triphenylphosphine; at 20 ℃; for 0.1h; Ionic liquid;

DOI:10.1080/00304940802711127

upstream raw materials:

propan-1-ol

propene

Dipropyl ether

acetyl iodide

Downstream raw materials:

4-propyl-morpholine

4-s-propylpyridine

2-isopropylpyridine

N-isobutyl-N-propylamine

Refernces

• 1、 Coskun, Timur,Conifer, Christopher M.,Stevenson, Laura C.,Britovsek, George J. P.. "Carbodeoxygenation of biomass: The carbonylation of glycerol and higher polyols to monocarboxylic acids". . p. 6840 - 6844. Retrieved 2013.
• 2、 Angeletti, Enrico,Tundo, Pietro,Venturello, Paolo. "Catalytic Halide Exchange in Hydrocarbons Promoted by Aluminas Coated with Phosphonium Salts". . p. 1127 - 1128. Retrieved 1980.
• 3、 Povlock. "-". . p. 4131. Retrieved 1967.
• 4、 Wang, Xiaochen,Zhu, Binbing,Dong, Jianyang,Tian, Hao,Liu, Yuxiu,Song, Hongjian,Wang, Qingmin. "Visible-light-mediated multicomponent reaction for secondary amine synthesis". . p. 5028 - 5031. Retrieved 2021.
• 5、 Vlasova,Grigor'Eva, O. Yu.,Voronkov. "Reactions of acetyl iodide with triethylsilylalkyl propyl sulfides". . . Retrieved 2013.
• 6、 Robbins, Daniel W.,Hartwig, John F.. "Sterically controlled alkylation of arenes through iridium-catalyzed C-H borylation". supporting information. p. 933 - 937. Retrieved 2013/02/25.