4(1H)-Pyridinone, 2-methyl-5-(phenylmethoxy)-1-[2-(1-piperidinyl)ethyl]-

Base Information

Chemical Name:4(1H)-Pyridinone, 2-methyl-5-(phenylmethoxy)-1-[2-(1-piperidinyl)ethyl]-
CAS No.:502689-86-3
Molecular Formula:C₂₀H₂₆N₂O₂
Molecular Weight:326.439
Hs Code.:
DSSTox Substance ID:DTXSID20455972
Mol file:502689-86-3.mol

Synonyms:4(1H)-Pyridinone, 2-methyl-5-(phenylmethoxy)-1-[2-(1-piperidinyl)ethyl]-;502689-86-3;DTXSID20455972

Suppliers and Price of 4(1H)-Pyridinone, 2-methyl-5-(phenylmethoxy)-1-[2-(1-piperidinyl)ethyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4(1H)-Pyridinone, 2-methyl-5-(phenylmethoxy)-1-[2-(1-piperidinyl)ethyl]-

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:326.199428076
Heavy Atom Count:24
Complexity:486

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=O)C(=CN1CCN2CCCCC2)OCC3=CC=CC=C3

Technology Process of 4(1H)-Pyridinone, 2-methyl-5-(phenylmethoxy)-1-[2-(1-piperidinyl)ethyl]-

There total 4 articles about 4(1H)-Pyridinone, 2-methyl-5-(phenylmethoxy)-1-[2-(1-piperidinyl)ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 27578-60-5
1-(2-aminoethyl)piperidine

: 100397-13-5
5-(benzyloxy)-2-methyl-4H-pyran-4-one

: 502689-86-3
5-benzyloxy-2-methyl-1-(2-piperidin-1-yl-ethyl)-1H-pyridin-4-one

Guidance literature:: In ethanol; for 40h; Heating;
DOI:10.1016/S0223-5234(02)01390-9

Reference yield:

: 644-46-2
allomaltol

: 502689-86-3
5-benzyloxy-2-methyl-1-(2-piperidin-1-yl-ethyl)-1H-pyridin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / NaOH / methanol; H₂O / 8 h / Heating

2: 85 percent / ethanol / 40 h / Heating

With sodium hydroxide; In methanol; ethanol; water;
DOI:10.1016/S0223-5234(02)01390-9

Reference yield:

: 501-30-4,123712-78-7
5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

: 502689-86-3
5-benzyloxy-2-methyl-1-(2-piperidin-1-yl-ethyl)-1H-pyridin-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: 72 percent / SOCl₂ / 2 h / 20 °C

2: 64 percent / Zn dust; HCl / H₂O / 4 h / 70 - 80 °C

3: 76 percent / NaOH / methanol; H₂O / 8 h / Heating

4: 85 percent / ethanol / 40 h / Heating

With hydrogenchloride; sodium hydroxide; thionyl chloride; zinc; In methanol; ethanol; water;
DOI:10.1016/S0223-5234(02)01390-9