100397-13-5

Basic information

• Product Name: 4H-Pyran-4-one, 2-methyl-5-(phenylmethoxy)-
• CAS NO: 100397-13-5
• Molecular Formula: C13H12O3
• Molecular Weight: 216.236
• Mol File: 100397-13-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 4H-Pyran-4-one, 2-methyl-5-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Pyran-4-one, 2-methyl-5-(phenylmethoxy)-(100397-13-5)
• EPA Substance Registry System: 4H-Pyran-4-one, 2-methyl-5-(phenylmethoxy)-(100397-13-5)

Safety Data

• Hazardous Substances Data: 100397-13-5(Hazardous Substances Data)

Usage

General Description

The chemical 4H-Pyran-4-one, 2-methyl-5-(phenylmethoxy)-, also known as methyl 5-(phenylmethoxy)-2-pyron, is a pyranone compound with a methyl group and a phenylmethoxy substituent. It is used in organic synthesis as a building block for the production of various pharmaceuticals and agrochemicals. The compound has been studied for its potential biological activities, including antioxidant and anticancer properties. It has also been investigated for its potential use in the development of new materials and as a flavoring agent in the food industry.

Upstream product

• 644-46-2 allomaltol 
• 100-39-0 benzyl bromide 
• 15771-06-9 5-benzyloxy-2-hydroxymethyl-4H-pyran-4-one 
• 89539-54-8 5-(benzyloxy)-2-(chloromethyl)-4H-pyran-4-one 
• 100-44-7 benzyl chloride 
• 7559-81-1 chlorokojic acid 
• 501-30-4 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 

Downstream Products

• 502689-89-6 5-benzyloxy-2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-pyridin-4-one 
• 502689-87-4 5-benzyloxy-2-methyl-1-(2-pyridin-2-yl-ethyl)-1H-pyridin-4-one 
• 1333331-94-4 5-(benzyloxy)-1-biphenyl-3-yl-2-methylpyridin-4(1H)-one 
• 1333331-93-3 1-(1H-benzimidazol-4-yl)-5-hydroxy-2-methylpyridin-4(1H)-one 
• 1333331-92-2 1-(1H-benzimidazol-4-yl)-5-(benzyloxy)-2-methylpyridin-4(1H)-one 
• 1333331-61-5 1-[1-(2-chloro-6-fluorobenzyl)-1H-benzimidazol-4-yl]-5-hydroxy-2-methylpyridin-4(1H)-one 
• 1333329-07-9 1-biphenyl-3-yl-5-hydroxy-2-methylpyridin-4(1H)-one 
• 1333331-95-5 1-biphenyl-3-yl-5-[(4-methoxybenzyl)oxy]-2-methylpyridin-4(1H)-one 
• 1333331-63-7 1-biphenyl-3-yl-2-[2-(5-fluoro-2-methoxypyridin-3-yl)-2-hydroxyethyl]-5-hydroxypyridin-4(1H)-one 
• 60403-96-5 CP69 

Relevant articles and documents

Design, synthesis and biological evaluation of hydroxypyridinone-coumarin hybrids as multimodal monoamine oxidase B inhibitors and iron chelates against Alzheimer's disease

A series of hybrids of hydroxypyridinone and coumarin were rationally designed, synthesized and biologically evaluated for their iron ion chelating and MAO-B inhibitory activities. Most of the compounds displayed excellent iron ion chelating effects and moderate to good anti-MAO-B activities. Compound 27a exhibited the most potent activity against MAO-B, with an IC50 value of 14.7 nM. Importantly, 27a showed good U251 cell protective effect and significantly ameliorated the cognitive dysfunction of scopolamine-induced AD mice. Moreover, molecular docking was performed to elucidate the probable ligand-receptor interaction, and the structure-activity relationships were also summarized.

ALA hybrid 3-hydroxypyridone derivative as well as preparation method and application thereof

The invention designs and synthesizes a novel anti-tumor active compound with iron chelating property and photosensitive activity based on the principles of reasonable drug design, drug-likeness and the like. The invention aims to provide a preparation me

Coumarin hybrid pyridinone amide derivative with potential anti-AD activity and preparation method and application of derivative

The invention discloses a coumarin hybrid pyridinone amide derivative and a preparation method and application thereof. The coumarin hybrid pyridinone amide derivative and pharmacologically acceptablesalt thereof are shown in the formula (I) and the formula (II), and the derivative can be used for preparing drugs for resisting the Alzheimer's disease, the Parkinson's disease or treating other diseases or symptoms by suppressing monoamine oxidase, chelating metallic iron ions, resisting A and resisting oxidation.