Deoxypodophyllotoxin

Base Information

Chemical Name:Deoxypodophyllotoxin
CAS No.:19186-35-7
Molecular Formula:C22H22O7
Molecular Weight:398.4059
Hs Code.:
NSC Number:403148
UNII:45NR8XYU1L
DSSTox Substance ID:DTXSID701019944
Nikkaji Number:J16.374K
Wikidata:Q27106380
Metabolomics Workbench ID:143423
ChEMBL ID:CHEMBL63970
Mol file:19186-35-7.mol

Synonyms:deoxypicropodophyllin;deoxypodophyllotoxin;deoxypodophyllotoxin, (5alpha,5aalpha,8aalpha)-(+-)-isomer;deoxypodophyllotoxin, (5alpha,5aalpha,8abeta)-(+-)-isomer;deoxypodophyllotoxin, (5R-(5alpha,5aalpha,8aalpha))-isomer;deoxypodophyllotoxin, (5R-(5alpha,5aalpha,8abeta))-isomer;deoxypodophyllotoxin, (5R-(5alpha,5abeta,8aalpha))-isomer;deoxypodophyllotoxin, (5R-(5alpha,5abeta,8abeta))-isomer;isoanthricin;isodeoxypodophyllotoxin

Suppliers and Price of Deoxypodophyllotoxin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
4-Deoxypodophyllotoxin
100mg
$ 460.00

TRC
4-Deoxypodophyllotoxin
1g
$ 1455.00

Medical Isotopes, Inc.
4-Deoxypodophyllotoxin
1 g
$ 2200.00

Crysdot
Deoxypodophyllotoxin 97%
5mg
$ 730.00

ChemScene
Deoxypodophyllotoxin 99.86%
10mg
$ 686.00

ChemScene
Deoxypodophyllotoxin 99.86%
5mg
$ 403.00

Biosynth Carbosynth
4-Deoxypodophyllotoxin
10 mg
$ 100.00

Biosynth Carbosynth
4-Deoxypodophyllotoxin
5 mg
$ 65.00

Biosynth Carbosynth
4-Deoxypodophyllotoxin
25 mg
$ 150.00

Biosynth Carbosynth
4-Deoxypodophyllotoxin
100 mg
$ 400.00

Total 37 raw suppliers

Chemical Property of Deoxypodophyllotoxin

Chemical Property:

Melting Point:168 °C
Boiling Point:564.5°Cat760mmHg
Flash Point:247°C
PSA：72.45000
Density:1.304g/cm³
LogP:2.91830
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:398.13655304
Heavy Atom Count:29
Complexity:598

Purity/Quality:

99%, ^*data from raw suppliers

4-Deoxypodophyllotoxin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1OC)OC)C2C3C(CC4=CC5=C(C=C24)OCO5)COC3=O
Isomeric SMILES:COC1=CC(=CC(=C1OC)OC)[C@H]2[C@@H]3[C@@H](CC4=CC5=C(C=C24)OCO5)COC3=O
Uses 4-Deoxypodophyllotoxin is a medicinal herb product isolated from Anthriscus sylvestris Hoffm. It is well known for its antitumor, antiviral, and anti-inflammatory activities. 4-Deoxypodophyllotoxin wa s also shown to inhibit the passive cutaneous anaphylaxis reaction.

Technology Process of Deoxypodophyllotoxin

There total 168 articles about Deoxypodophyllotoxin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 40456-50-6,17301-91-6,61091-56-3,72690-16-5,96745-44-7,119066-80-7,128049-89-8,139560-31-9
yatein

: 477-51-0,6258-33-9,17187-81-4,17301-90-5,19186-35-7,24150-39-8,31892-96-3,55568-81-5,64550-41-0,69222-20-4,75171-57-2,83023-41-0,100348-38-7
deoxypodophyllotoxin

Guidance literature:: With ferrous(II) sulfate heptahydrate; ATGGGCAGCACCGCGCCGCTGCGTTTCCCGGTTATCGATTTGAGCATGAAGAACCTGAAACCTGGAACCACATCATGGAACAGCGTACGCACTCAGGTGCGTGAAGCTTTGGAAGAATATGGTTGCTTTGAAGCCGTTATTGATGCGGTTTCCCCAGAGTTGCAAAAAGCTGTCTGCAACAAGGGGCACGAACTGTTAAATTTACCGCTGGAGACCAAGATGCTTAATGGTAATAAGCCGGAGTACGATGGATTTACATCAATCCCGAACCTTAACGAAGGTATGGGTGTTGGCCGCATCACTGACTTAGAGAAGGTCGAACGTTTCACTAATCTGATGTGGCCTGAGGGGAACAAGGATTTTTGCGAAACAGTTTACTCCTATGGTAAGCGCATGGCAGAGGTTGACCATATTCTGAAGATGATGGTATTCGAATCTTTTGGTATGGAGAAACATTTTGACTCCTTCTGCGAAAGTACAAATTACTTGCTGCATTTCATGCGCTATCAACAACCCGGCAAAGACGGTCGCTCTCCCGCATTGAGTTTACACAAAGATAAATCTATCCTTACGATCGTCAACCAAAACGATGTAAAAGGACTGGAGTTCGAAACAAAGGATGGCGAATGGATTTTGCCAACAGCCGATAACCACATCGTATTACTTGGAGATTGCTTCATGGCTTGGAGTAACGGTCGCCTGCACTCTCCACTGCACCGTGTGACATTAGTGGCAAATCAGGCACGTTTGAGTACCTCCTCATTTAGCTTCCCAAAAGATATTATTGAGACACCGGCGGAATTGGTGGACGAGGAACATCCGCTTTTATTCAATCCCTTCGAGATCACCGAGCTTTTAGCCTACTGTTTTACAAAAGAAGGAGCCAAGGCGGTTTGCGATTTAAAGCAGTATAAAGCGTACACTGGAGCATGA; α-ketoglutaric acid disodium salt; ascorbic acid; In dimethyl sulfoxide; at 23 ℃; for 20h;
DOI:10.1002/anie.201904102

Reference yield: 45.0%

: 563-80-4
3-methyl-butan-2-one

: 477-48-5,477-49-6,55515-07-6,60660-51-7,64550-42-1,64937-82-2,86594-36-7,130322-38-2
podophyllotoxone

: 7α-[(2R)-2-hydroxy-3-methylbut-2-yl]epi-podophyllotoxin

: 7α-[(2S)-2-hydroxy-3-methylbut-2-yl]epi-podophyllotoxin

: 477-51-0,6258-33-9,17187-81-4,17301-90-5,19186-35-7,24150-39-8,31892-96-3,55568-81-5,64550-41-0,69222-20-4,75171-57-2,83023-41-0,100348-38-7
deoxypodophyllotoxin

: 518-28-5
podofilox

Guidance literature:: With titanium tetrachloride; zinc; In tetrahydrofuran; at -20 - -10 ℃; for 4h; Inert atmosphere;
DOI:10.1021/jm2017573

Reference yield: 45.0%

: 67-64-1
acetone

: 477-48-5,477-49-6,55515-07-6,60660-51-7,64550-42-1,64937-82-2,86594-36-7,130322-38-2
podophyllotoxone

: 7α-(2-hydroxyprop-2-yl)podophyllotoxin

: 7β-(2-hydroxyprop-2-yl)podophyllotoxin

: 477-51-0,6258-33-9,17187-81-4,17301-90-5,19186-35-7,24150-39-8,31892-96-3,55568-81-5,64550-41-0,69222-20-4,75171-57-2,83023-41-0,100348-38-7
deoxypodophyllotoxin

: 518-28-5
podofilox

Guidance literature:: With titanium tetrachloride; zinc; In tetrahydrofuran; at -20 - -10 ℃; for 4h; optical yield given as %de; Inert atmosphere;
DOI:10.1021/jm2017573