(S)-Suprofen

Base Information

Chemical Name:(S)-Suprofen
CAS No.:52780-12-8
Molecular Formula:C14H12 O3 S
Molecular Weight:260.313
Hs Code.:
European Community (EC) Number:258-175-6
UNII:TQ57I8046V
DSSTox Substance ID:DTXSID901317910
Nikkaji Number:J295.796E
Wikidata:Q27290142
ChEMBL ID:CHEMBL253766
Mol file:52780-12-8.mol

Synonyms:(S)-Suprofen;52780-12-8;(+)-Suprofen;Suprofen, (S)-;(2S)-2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid;NIOSH/CY1685650;TQ57I8046V;CY16856500;(+)-alpha-Methyl-4-(2-thienylcarbonyl)benzeneacetic acid;Benzeneacetic acid, alpha-methyl-4-(2-thienylcarbonyl)-, (S)-;(S)-(+)-suprofen;M5A;(S)-2-(4-(Thien-2-ylcarbonyl)phenyl)butyric acid;BIDD:GT0542;UNII-TQ57I8046V;CHEMBL253766;SCHEMBL5102821;DTXSID901317910;EINECS 258-175-6;LS-28963;EN300-27121321;Q27290142;(S)-alpha-methyl-4-(2-thienylcarbonyl)benzeneacetic acid;(.ALPHA.S)-.ALPHA.-METHYL-4-(2-THIENYLCARBONYL)BENZENEACETIC ACID;BENZENEACETIC ACID, .ALPHA.-METHYL-4-(2-THIENYLCARBONYL)-, (S)-;BENZENEACETIC ACID, .ALPHA.-METHYL-4-(2-THIENYLCARBONYL)-, (.ALPHA.S)-

Suppliers and Price of (S)-Suprofen

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (S)-Suprofen

Chemical Property:

Boiling Point:442.6°Cat760mmHg
Flash Point:221.5°C
PSA：82.61000
Density:1.29g/cm³
LogP:3.16720
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:260.05071541
Heavy Atom Count:18
Complexity:321

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=C(C=C1)C(=O)C2=CC=CS2)C(=O)O
Isomeric SMILES:C[C@@H](C1=CC=C(C=C1)C(=O)C2=CC=CS2)C(=O)O

Technology Process of (S)-Suprofen

There total 15 articles about (S)-Suprofen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 40828-46-4
2-[4-(thien-2-ylcarbonyl)phenyl]propanoic acid

: 52780-12-8
(S)-Suprofen

: 52780-13-9
(R)-Suprofen

Guidance literature:: With trifluoroacetic acid; In methanol; at 35 ℃; under 103432 Torr; Reagent/catalyst; Solvent; Resolution of racemate; Supercritical conditions;
DOI:10.1002/chir.22701

Reference yield:

: 132353-69-6,132437-28-6
(S)-2-[4-(2-Thiophen-2-yl-[1,3]dioxolan-2-yl)-phenyl]-propionic acid 2'-hydroxy-[1,1']binaphthalenyl-2-yl ester

: 52780-12-8
(S)-Suprofen

: 52780-13-9
(R)-Suprofen

Guidance literature:: With hydrogenchloride; lithium hydroxide; Yield given. Multistep reaction;
DOI:10.1016/S0040-4039(00)97115-6

Reference yield:

: (3S)-4,4-dimethyl-2-oxo-1-phenylpyrrolidin-3-yl α-<4-(2-thenoyl)phenyl>propionate

: 52780-12-8
(S)-Suprofen

: 52780-13-9
(R)-Suprofen

Guidance literature:: With hydrogenchloride; acetic acid; for 2.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Heating;
DOI:10.1016/0957-4166(95)00110-B