3-bromo-2-(4-methoxyphenyl)-1H-quinolin-4-one

Base Information

Chemical Name:3-bromo-2-(4-methoxyphenyl)-1H-quinolin-4-one
CAS No.:502841-12-5
Molecular Formula:C₁₆H₁₂BrNO₂
Molecular Weight:330.181
Hs Code.:
DSSTox Substance ID:DTXSID201277416
Nikkaji Number:J1.846.965K

Synonyms:502841-12-5;DTXSID201277416;3-Bromo-2-(4-methoxyphenyl)-4-quinolinol

Suppliers and Price of 3-bromo-2-(4-methoxyphenyl)-1H-quinolin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-bromo-2-(4-methoxyphenyl)-1H-quinolin-4-one

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:329.00514
Heavy Atom Count:20
Complexity:413

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=C(C(=O)C3=CC=CC=C3N2)Br

Technology Process of 3-bromo-2-(4-methoxyphenyl)-1H-quinolin-4-one

There total 2 articles about 3-bromo-2-(4-methoxyphenyl)-1H-quinolin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 3813-92-1
2-(4-methoxyphenyl)-1,4-dihydro-4-oxoquinoline

: 502841-12-5,476681-56-8
3-bromo-2-(4'-methoxyphenyl)quinolin-4(1H)-one

Guidance literature:: With pyridinium hydrobromide perbromide; In acetic acid; at 20 ℃; for 3h;
DOI:10.1002/jhet.5570430203

Reference yield: 56.0%

: 3-bromo-1-methanesulfonyl-2-(4-methoxy-phenyl)-2,3-dihydro-1H-quinolin-4-one

: 502841-12-5,476681-56-8
3-bromo-2-(4'-methoxyphenyl)quinolin-4(1H)-one

Guidance literature:: With dimethyl sulfoxide; at 130 - 140 ℃; for 5h;

Reference yield: 86.0%

: (4-methyl-2-oxo-4-vinyl-2,4-dihydro-1H-benzo[d][1,3]oxazin-6-yl)boronic acid

: 502841-12-5,476681-56-8
3-bromo-2-(4'-methoxyphenyl)quinolin-4(1H)-one

: 6-(2-(4-methoxyphenyl)-4-oxo-1,4-dihydroquinolin-3-yl)-4-methyl-4-vinyl-1H-benzo[d][1,3]oxazin-2(4H)-one

Guidance literature:: With C₃₀H₁₈Cl₂N₂O₄Pd; tetrabutylammomium bromide; potassium carbonate; In ethanol; at 60 ℃; Sealed tube; Microwave irradiation;
DOI:10.1039/c5ra15274g