Isocorydine hydrochloride

Base Information

• Chemical Name: Isocorydine hydrochloride
• CAS No.: 13552-72-2
• Molecular Formula: C₂₀H₂₃NO₄*ClH
• Molecular Weight: 377.868
• Mol file: 13552-72-2.mol

Synonyms:Isocorydine hydrochloride;66968-08-9;6a-alpha-APORPHIN-11-OL, 1,2,10-TRIMETHOXY-, HYDROCHLORIDE;(6aS)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium-11-ol;chloride;LS-21505

Chemical Property of Isocorydine hydrochloride

Chemical Property:

• Melting Point: 216-220 °C(lit.)
• Boiling Point: 506.1 °C at 760 mmHg
• Flash Point: 259.9 °C
• PSA: 51.16000
• Density: 1.222 g/cm3
• LogP: 3.91000
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 377.1393859
• Heavy Atom Count: 26
• Complexity: 475

Purity/Quality:

98%,99%, ^*data from raw suppliers

IsocorydineHydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Safety Statements: 16-23-45-22-7

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[NH+]1CCC2=CC(=C(C3=C2C1CC4=C3C(=C(C=C4)OC)O)OC)OC.[Cl-]
• Isomeric SMILES: C[NH+]1CCC2=CC(=C(C3=C2[C@@H]1CC4=C3C(=C(C=C4)OC)O)OC)OC.[Cl-]
• Uses: Isocorydine Hydrochloride is the hydrochloric acid of Isocorydine(I797000) which is an alkaloid inhibitor of eukaryotic kinases.

Technology Process of Isocorydine hydrochloride

There total 1 articles about Isocorydine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

isocorydine (475-67-2) → isocorydine hydrochloride (13552-72-2)

Guidance literature:

With hydrogenchloride; In chloroform-d1; water;

DOI:10.1016/j.phytochem.2009.11.010

upstream raw materials:

isocorydine

Refernces