Technology Process of 5,8,11-Trioxa-2-azatridecanedioic acid, 1-(1,1-dimethylethyl)
13-(pentafluorophenyl) ester
There total 6 articles about 5,8,11-Trioxa-2-azatridecanedioic acid, 1-(1,1-dimethylethyl)
13-(pentafluorophenyl) ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2003.12.079
- Guidance literature:
-
Multi-step reaction with 6 steps
1: Et3N / diethyl ether
2: NaN3 / ethanol / Heating
3: 80 percent / CrO3; aq. H2SO4 / acetone
4: 100 percent / H2 / Pd/C / ethanol
5: 36 percent / aq. NaOH / tetrahydrofuran
6: 80 percent / EDCI / dimethylformamide
With
chromium(VI) oxide; sodium hydroxide; sodium azide; sulfuric acid; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; ethanol; N,N-dimethyl-formamide; acetone;
3: Jones oxidation;
DOI:10.1016/j.bmcl.2003.12.079
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 80 percent / CrO3; aq. H2SO4 / acetone
2: 100 percent / H2 / Pd/C / ethanol
3: 36 percent / aq. NaOH / tetrahydrofuran
4: 80 percent / EDCI / dimethylformamide
With
chromium(VI) oxide; sodium hydroxide; sulfuric acid; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide; acetone;
1: Jones oxidation;
DOI:10.1016/j.bmcl.2003.12.079
