N-(4-methoxyphenyl)-2,4-dichlorobenzenecarboxamidine

Base Information

Chemical Name:N-(4-methoxyphenyl)-2,4-dichlorobenzenecarboxamidine
CAS No.:505073-85-8
Molecular Formula:C14H12Cl2N2O
Molecular Weight:295.168
Hs Code.:
DSSTox Substance ID:DTXSID70465566
Mol file:505073-85-8.mol

Synonyms:N-(4-methoxyphenyl)-2,4-dichlorobenzenecarboxamidine;505073-85-8;SCHEMBL4517016;DTXSID70465566;HZUGXKOBWNOCKU-UHFFFAOYSA-N

Suppliers and Price of N-(4-methoxyphenyl)-2,4-dichlorobenzenecarboxamidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-(4-methoxyphenyl)-2,4-dichlorobenzenecarboxamidine

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:294.0326684
Heavy Atom Count:19
Complexity:317

Purity/Quality:: 99% ，98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)N=C(C2=C(C=C(C=C2)Cl)Cl)N

Technology Process of N-(4-methoxyphenyl)-2,4-dichlorobenzenecarboxamidine

There total 2 articles about N-(4-methoxyphenyl)-2,4-dichlorobenzenecarboxamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 6574-98-7
2,4-dichlorobenzylnitrile

: 505073-85-8
2,4-dichloro-N-(4-methoxyphenyl)benzenecarboximidamide

Guidance literature:: 4-methoxy-aniline; With ethylmagnesium bromide; In tetrahydrofuran; for 0.5h;

2,4-dichlorobenzylnitrile; In tetrahydrofuran; at 20 ℃;

Reference yield: 88.0%

: 104-94-9
4-methoxy-aniline

: 6574-98-7
2,4-dichlorobenzylnitrile

: 505073-85-8
2,4-dichloro-N-(4-methoxyphenyl)benzenecarboximidamide

Guidance literature:: With sodium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 16h;
DOI:10.1021/jm040843r

Reference yield: 50.0%

: 505073-85-8
2,4-dichloro-N-(4-methoxyphenyl)benzenecarboximidamide

: 57332-84-0
3-bromo-2-oxo-butyric acid ethyl ester

: 505073-86-9
ethyl 2-(2,4-dichlorophenyl)-1-(4-methoxyphenyl)-5-methyl-1H-imidazole-4-carboxylate

Guidance literature:: 2,4-dichloro-N-(4-methoxyphenyl)benzenecarboximidamide; 3-bromo-2-oxo-butyric acid ethyl ester; With potassium carbonate; In tetrahydrofuran; at 20 ℃;

With acetic acid; for 1h; Heating / reflux;