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2,3,6,7,10,11,14,15,18,19,22,23-Dodecaazapentacosanedioic acid, 8,20-dimethyl-4,16-bis(1-methylethyl)-12,24-bis(2-methylpropyl)-5,9,13, 17,21-pentaoxo-3,7,11,15,19,23-hexakis(phenylmethyl)-, 1-(1,1-dimethylethyl) 25-methyl ester, (4S,8S,12S,16S,20S,24S)-

Base Information
  • Chemical Name:2,3,6,7,10,11,14,15,18,19,22,23-Dodecaazapentacosanedioic acid, 8,20-dimethyl-4,16-bis(1-methylethyl)-12,24-bis(2-methylpropyl)-5,9,13, 17,21-pentaoxo-3,7,11,15,19,23-hexakis(phenylmethyl)-, 1-(1,1-dimethylethyl) 25-methyl ester, (4S,8S,12S,16S,20S,24S)-
  • CAS No.:509150-82-7
  • Molecular Formula:C76H104N12O9
  • Molecular Weight:1329.74
  • Hs Code.:
2,3,6,7,10,11,14,15,18,19,22,23-Dodecaazapentacosanedioic acid,
8,20-dimethyl-4,16-bis(1-methylethyl)-12,24-bis(2-methylpropyl)-5,9,13,
17,21-pentaoxo-3,7,11,15,19,23-hexakis(phenylmethyl)-,
1-(1,1-dimethylethyl) 25-methyl ester, (4S,8S,12S,16S,20S,24S)-

Synonyms:

Suppliers and Price of 2,3,6,7,10,11,14,15,18,19,22,23-Dodecaazapentacosanedioic acid, 8,20-dimethyl-4,16-bis(1-methylethyl)-12,24-bis(2-methylpropyl)-5,9,13, 17,21-pentaoxo-3,7,11,15,19,23-hexakis(phenylmethyl)-, 1-(1,1-dimethylethyl) 25-methyl ester, (4S,8S,12S,16S,20S,24S)-
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Chemical Property of 2,3,6,7,10,11,14,15,18,19,22,23-Dodecaazapentacosanedioic acid, 8,20-dimethyl-4,16-bis(1-methylethyl)-12,24-bis(2-methylpropyl)-5,9,13, 17,21-pentaoxo-3,7,11,15,19,23-hexakis(phenylmethyl)-, 1-(1,1-dimethylethyl) 25-methyl ester, (4S,8S,12S,16S,20S,24S)-
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Technology Process of 2,3,6,7,10,11,14,15,18,19,22,23-Dodecaazapentacosanedioic acid, 8,20-dimethyl-4,16-bis(1-methylethyl)-12,24-bis(2-methylpropyl)-5,9,13, 17,21-pentaoxo-3,7,11,15,19,23-hexakis(phenylmethyl)-, 1-(1,1-dimethylethyl) 25-methyl ester, (4S,8S,12S,16S,20S,24S)-

There total 6 articles about 2,3,6,7,10,11,14,15,18,19,22,23-Dodecaazapentacosanedioic acid, 8,20-dimethyl-4,16-bis(1-methylethyl)-12,24-bis(2-methylpropyl)-5,9,13, 17,21-pentaoxo-3,7,11,15,19,23-hexakis(phenylmethyl)-, 1-(1,1-dimethylethyl) 25-methyl ester, (4S,8S,12S,16S,20S,24S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With 4-methyl-morpholine; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; at 0 - 20 ℃; for 24h;
DOI:10.1002/hlca.200390342
Guidance literature:
Multi-step reaction with 5 steps
1.1: NaOH; water / 20 °C
1.2: 86 percent / NaBH4 / 0 °C
2.1: Et4NOH / methanol
2.2: 65 percent / CH2Cl2 / cooling
3.1: 2.15 g / N-methylmorpholine; HATU / dimethylformamide / 46 h / 0 - 20 °C
4.1: 100 percent / LiOH; water / methanol / 20 °C
5.1: 182 mg / N-methylmorpholine; HATU; BOPCl / CH2Cl2 / 24 h / 0 - 20 °C
With 4-methyl-morpholine; lithium hydroxide; sodium hydroxide; water; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; tetraethylammonium hydroxide; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/hlca.200390342
Guidance literature:
Multi-step reaction with 4 steps
1.1: Et4NOH / methanol
1.2: 65 percent / CH2Cl2 / cooling
2.1: 2.15 g / N-methylmorpholine; HATU / dimethylformamide / 46 h / 0 - 20 °C
3.1: 100 percent / LiOH; water / methanol / 20 °C
4.1: 182 mg / N-methylmorpholine; HATU; BOPCl / CH2Cl2 / 24 h / 0 - 20 °C
With 4-methyl-morpholine; lithium hydroxide; water; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; tetraethylammonium hydroxide; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/hlca.200390342
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