1,3-Bis(4-aminophenyl)urea

Base Information

• Chemical Name: 1,3-Bis(4-aminophenyl)urea
• CAS No.: 4550-72-5
• Molecular Formula: C13H14 N4 O
• Molecular Weight: 242.28
• Hs Code.: 2924299090
• Mol file: 4550-72-5.mol

Synonyms:Carbanilide,4,4'-diamino- (6CI,7CI,8CI); 1,3-Bis(4-aminophenyl)urea;1,3-Bis(p-aminophenyl)urea; 4,4'-Diamino-N,N'-diphenylurea;4,4'-Diaminocarbanilide; 4,4'-Diaminodiphenylurea; N,N'-Bis(4-aminophenyl)urea;NSC 15364

Chemical Property of 1,3-Bis(4-aminophenyl)urea

Chemical Property:

• Vapor Pressure: 5.1E-06mmHg at 25°C
• Boiling Point: 381.4°Cat760mmHg
• Flash Point: 184.5°C
• PSA: 93.17000
• Density: 1.389g/cm³
• LogP: 3.80340

Purity/Quality:

97% ^*data from raw suppliers

NSC15364 >98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1,3-Bis(4-Aminophenyl)Urea (cas# 4550-72-5) is used in the colored anti-caking agent containing water-soluble polymer for preventing fertilizer agglomeration and its preparation method.

Technology Process of 1,3-Bis(4-aminophenyl)urea

There total 12 articles about 1,3-Bis(4-aminophenyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

bis-N,N'-(4-nitrophenyl)urea (587-90-6) → N,N'-bis(4-aminophenyl)urea (4550-72-5)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 22h; atmospheric pressure;

DOI:10.1021/jm7013088

Reference yield: 73.09%

urea (57-13-6) + 1,4-phenylenediamine (106-50-3) → N,N'-bis(4-aminophenyl)urea (4550-72-5)

Guidance literature:

With sodium hydrogensulfite; acetic acid; In water; at 102 ℃; for 40h;

Reference yield:

4-nitro-aniline (100-01-6,104810-17-5) → N,N'-bis(4-aminophenyl)urea (4550-72-5)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dioxane; benzene / 12 h / Heating

2: H₂ / 10percent Pd/C / dimethylformamide / 25 °C / 2280 Torr

With hydrogen; triethylamine; palladium on activated charcoal; In 1,4-dioxane; N,N-dimethyl-formamide; benzene;

DOI:10.1021/jm00149a032

upstream raw materials:

bis-N,N'-(4-nitrophenyl)urea

N,N'-((carbonylbis(azanediyl))bis(4,1-phenylene))diacetamide

aniline yellow

urea

Downstream raw materials:

6,6'-dihydroxy-3,3'-(4,4'-ureylene-bis-phenylazo)-di-benzoic acid

1,3-Bis-[4-(4,6-diamino-2,2-dimethyl-2H-[1,3,5]triazin-1-yl)-phenyl]-urea; hydrochloride

1,3-bis(4-[2,3-di(tert-butoxycarbonyl)guanidino]phenyl)urea

1,3-bis(4-[1,3-di(tert-butoxycarbonyl)-2-imidazolidinylimino]phenyl)urea