4,6-Dichloro-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidin-2-amine

Base Information

Chemical Name:4,6-Dichloro-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidin-2-amine
CAS No.:51323-79-6
Molecular Formula:C14H15Cl2N3O3
Molecular Weight:344.197
Hs Code.:
DSSTox Substance ID:DTXSID90505857
Wikidata:Q82361234
Mol file:51323-79-6.mol

Synonyms:51323-79-6;4,6-Dichloro-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidin-2-amine;SCHEMBL12496384;DTXSID90505857

Suppliers and Price of 4,6-Dichloro-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4,6-Dichloro-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidin-2-amine

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:343.0490467
Heavy Atom Count:22
Complexity:327

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1OC)OC)CC2=C(N=C(N=C2Cl)N)Cl

Technology Process of 4,6-Dichloro-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidin-2-amine

There total 1 articles about 4,6-Dichloro-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51323-79-6
2-amino-4,6-dichloro-5-(3,4,5-trimethoxybenzyl)pyrimidine

Guidance literature:: Acetylaminverb. (4), PCl3 und alkal. Hydrolyse.;

Reference yield:

: 51323-79-6
2-amino-4,6-dichloro-5-(3,4,5-trimethoxybenzyl)pyrimidine

: 30563-87-2
2,4-diamino-5-(3,4,5-trimethoxybenzyl)-6-chloropyrimidine

Guidance literature:: With ammonia; In ethanol; at 117 ℃; for 7h;
DOI:10.1021/jm00179a012

Reference yield:

: 51323-79-6
2-amino-4,6-dichloro-5-(3,4,5-trimethoxybenzyl)pyrimidine

: 73576-36-0
2,4-diamino-5-(3,4,5-trimethoxybenzyl)-6-(N,N-dimethylamino)pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 0.8 g / NH₃ / ethanol / 7 h / 117 °C

2: 375 mg / ethanol / 4 h / 132 °C

With ammonia; In ethanol;
DOI:10.1021/jm00179a012