N-(2,6-dimethylphenyl)-4-hydroxybenzamide

Base Information

Chemical Name:N-(2,6-dimethylphenyl)-4-hydroxybenzamide
CAS No.:51616-07-0
Molecular Formula:C15H15NO2
Molecular Weight:241.29
Hs Code.:
DSSTox Substance ID:DTXSID10442811
Nikkaji Number:J1.006.240C
Wikidata:Q82260320
ChEMBL ID:CHEMBL112766
Mol file:51616-07-0.mol

Synonyms:N-(2,6-dimethylphenyl)-4-hydroxybenzamide;51616-07-0;Benzamide, N-(2,6-dimethylphenyl)-4-hydroxy-;CHEMBL112766;SCHEMBL9522743;DTXSID10442811;AFSOCTSNUFCJTG-UHFFFAOYSA-N;AKOS000211403

Suppliers and Price of N-(2,6-dimethylphenyl)-4-hydroxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of N-(2,6-dimethylphenyl)-4-hydroxybenzamide

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:241.110278721
Heavy Atom Count:18
Complexity:274

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=CC=C1)C)NC(=O)C2=CC=C(C=C2)O

Technology Process of N-(2,6-dimethylphenyl)-4-hydroxybenzamide

There total 7 articles about N-(2,6-dimethylphenyl)-4-hydroxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 97769-01-2
N-(2,6-dimethylphenyl)-4-methoxybenzamide

: 51616-07-0
4-Hydroxy-N-(2,6-dimethylphenyl)benzamide

Guidance literature:: With boron tribromide; In dichloromethane; water;

Reference yield:

: 64594-44-1
4-Nitro-N-(2,6-dimethylphenyl)benzamide

: 51616-07-0
4-Hydroxy-N-(2,6-dimethylphenyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / cyclohexene / 10percent Pd/C / propan-2-ol / 8 h / Heating

2: 1.) NaNO₂, aq. H₂SO₄, 2.) aq. H₂SO₄ / 1.) from 0 deg C to 5 deg C, 2.) reflux, 30 min

With sulfuric acid; cyclohexene; sodium nitrite; palladium on activated charcoal; In isopropyl alcohol;
DOI:10.1021/jm9608772

Reference yield:

: 122-04-3
4-nitro-benzoyl chloride

: 51616-07-0
4-Hydroxy-N-(2,6-dimethylphenyl)benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / pyridine / tetrahydrofuran / 3 h / Ambient temperature

2: 91 percent / cyclohexene / 10percent Pd/C / propan-2-ol / 8 h / Heating

3: 1.) NaNO₂, aq. H₂SO₄, 2.) aq. H₂SO₄ / 1.) from 0 deg C to 5 deg C, 2.) reflux, 30 min

With pyridine; sulfuric acid; cyclohexene; sodium nitrite; palladium on activated charcoal; In tetrahydrofuran; isopropyl alcohol;
DOI:10.1021/jm9608772