(-)-Chlorpheniramine maleate

Base Information

• Chemical Name: (-)-Chlorpheniramine maleate
• CAS No.: 23095-76-3
• Molecular Formula: C20H23ClN2O4
• Molecular Weight: 390.867
• Hs Code.: 2933399090
• UNII: 5T8587JTSU
• DSSTox Substance ID: DTXSID60904611
• Mol file: 23095-76-3.mol

Synonyms:(-)-Chlorpheniramine maleate;23095-76-3;l-Chlorpheniramine maleate;(R)-(-)-Chlorpheniramine maleate;CHLORPHENIRAMINE (S) MALEATE;(R)-Chlorpheniramine Maleate Salt;5T8587JTSU;Chlorpheniramine maleate, (-)-;(R)-3-(4-chlorophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine maleate;UNII-5T8587JTSU;SPECTRUM1500183;DTXSID60904611;DBAKFASWICGISY-HFNHQGOYSA-N;HMS1920K21;HMS2091E04;Pharmakon1600-01500183;(-)-2-(p-Chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine maleate;CCG-38948;NSC756684;CHLORPHENAMINE MALEATE, (R)-;AKOS040745431;CHLORPHENIRAMINE MALEATE, (R)-;2-Pyridinepropanamine, gamma-(4-chlorophenyl)-N,N-dimethyl-, (R)-, (Z)-2-butenedioate (1:1);Pyridine, 2-(p-chloro-alpha-(2-(dimethylamino)ethyl)benzyl)-, maleate (1:1), (-)-;PD119097;EN300-26256432;(2Z)-but-2-enedioic acid;[(3R)-3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine;(R)-gamma-(4-chlorophenyl)-N,N-dimethyl-2-Pyridinepropanamine (Z)-2-butenedioate (1:1);(Z)-but-2-enedioic acid;(3R)-3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine;Pyridine,2-(p-chloro-alpha-(2-(dimethylamino)ethyl)benzyl)-,maleate(1:1),(-)-;(gammaR) -gamma- (4- chlorophenyl) - N, N- dimethyl- 2- Pyridinepropanamine (2Z) - 2- butenedioate (1:1);2-PYRIDINEPROPANAMINE, .GAMMA.-(4-CHLOROPHENYL)-N,N-DIMETHYL-, (.GAMMA.R)-, (2Z)-2-BUTENEDIOATE (1:1);2-PYRIDINEPROPANAMINE, .GAMMA.-(4-CHLOROPHENYL)-N,N-DIMETHYL-, (R)-, (2Z)-2-BUTENEDIOATE (1:1);2-PYRIDINEPROPANAMINE, .GAMMA.-(4-CHLOROPHENYL)-N,N-DIMETHYL-, (R)-, (Z)-2-BUTENEDIOATE (1:1);PYRIDINE, 2-(P-CHLORO-.ALPHA.-(2-(DIMETHYLAMINO)ETHYL)BENZYL)-, MALEATE (1:1), (-)-

Chemical Property of (-)-Chlorpheniramine maleate

Chemical Property:

• Vapor Pressure: 5.88E-07mmHg at 25°C
• Boiling Point: 395.3 °C at 760 mmHg
• Flash Point: 192.8 °C
• PSA: 90.73000
• Density: g/cm³
• LogP: 3.53040
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform (Slightly), DMF (Slightly), Methanol (Slightly)
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 390.1346349
• Heavy Atom Count: 27
• Complexity: 368

Purity/Quality:

99% ^*data from raw suppliers

(R)-(-)-ChlorpheniramineMaleate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2.C(=CC(=O)O)C(=O)O
• Isomeric SMILES: CN(C)CC[C@H](C1=CC=C(C=C1)Cl)C2=CC=CC=N2.C(=C\C(=O)O)\C(=O)O
• Uses: The R-enantiomer of Chlorpheniramine (C424300). Antihistaminic.

Technology Process of (-)-Chlorpheniramine maleate

There total 1 articles about (-)-Chlorpheniramine maleate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chlorphenamine maleate (113-92-8) → dextrochlorpheniramine maleate (2438-32-6) + (-)-Chlorpheniramine maleate (23095-76-3)

Guidance literature:

With sodium dihydrogenphosphate; phosphoric acid; In methanol; water; pH=2.75; Reagent/catalyst; Ionic liquid; Resolution of racemate;

DOI:10.1002/chir.22168

Reference yield:

(-)-Chlorpheniramine maleate (23095-76-3) → R-(-)-monodesmethylchlorpheniramine

Guidance literature:

With α-D-glucose 6-phosphate; Wistar rat liver microsomes; NADP; In phosphate buffer; at 37 ℃; for 0.5h; Further Variations:; Reaction partners; Enzyme kinetics; Enzymatic reaction;

DOI:10.1111/j.2042-7158.1997.tb06791.x

upstream raw materials:

chlorphenamine maleate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 23095-76-3 (-)-CHLORPHENIRAMINE MALEATE

Send

Send

Metric Ton KG G Pound L ML

Send

Send