1-Benzyl-4-phenylpiperidin-4-ol

Base Information

Chemical Name:1-Benzyl-4-phenylpiperidin-4-ol
CAS No.:63843-83-4
Molecular Formula:C18H21NO
Molecular Weight:267.371
Hs Code.:2933399090
European Community (EC) Number:264-512-8
NSC Number:116051
DSSTox Substance ID:DTXSID60213290
Nikkaji Number:J83.613C
Wikidata:Q72442688
ChEMBL ID:CHEMBL230141
Mol file:63843-83-4.mol

Synonyms:1-Benzyl-4-phenylpiperidin-4-ol;63843-83-4;1-Benzyl-4-phenyl-4-piperidinol;4-Piperidinol, 1-benzyl-4-phenyl-;1-benzyl-4-hydroxy-4-phenylpiperidine;EINECS 264-512-8;BRN 0235839;CHEMBL230141;1-Benzyl-4-phenyl-piperidin-4-ol;1-benzyl-4-hydroxy-4-phenyl piperidine;NSC116051;D0TJ7R;Oprea1_173104;Oprea1_213406;F1446-0078;SCHEMBL1411499;DTXSID60213290;HMS1672E06;BCP13431;BDBM50210409;MFCD00598510;STK081775;4-phenyl-1-phenylmethyl-4-piperidinol;AKOS000541462;NSC 116051;NSC-116051;NCGC00245234-01;AM804182;LS-116845;FT-0698737;EN300-191780;A868011;AE-641/05503063;J-504300

Suppliers and Price of 1-Benzyl-4-phenylpiperidin-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-Benzyl-4-phenylpiperidin-4-ol 95%+
5g
$ 1442.00

Matrix Scientific
1-Benzyl-4-phenylpiperidin-4-ol 95%+
1g
$ 436.00

Matrix Scientific
1-Benzyl-4-phenylpiperidin-4-ol 95%+
2.500g
$ 953.00

Crysdot
1-Benzyl-4-phenylpiperidin-4-ol 95+%
5g
$ 589.00

American Custom Chemicals Corporation
1-BENZYL-4-PHENYLPIPERIDIN-4-OL 95.00%
5MG
$ 497.81

Alichem
1-Benzyl-4-phenylpiperidin-4-ol
5g
$ 523.20

Alichem
1-Benzyl-4-phenylpiperidin-4-ol
1g
$ 176.00

Alichem
1-Benzyl-4-phenylpiperidin-4-ol
25g
$ 1089.68

AK Scientific
1-Benzyl-4-phenylpiperidin-4-ol
2.5g
$ 1336.00

Total 29 raw suppliers

Chemical Property of 1-Benzyl-4-phenylpiperidin-4-ol

Chemical Property:

Vapor Pressure:5.39E-08mmHg at 25°C
Melting Point:107-109℃
Refractive Index:1.611
Boiling Point:425.4 °C at 760 mmHg
PKA:14.06±0.20(Predicted)
Flash Point:133.9 °C
PSA：23.47000
Density:1.135g/cm³
LogP:3.10810
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:267.162314293
Heavy Atom Count:20
Complexity:284

Purity/Quality:

97% ^*data from raw suppliers

1-Benzyl-4-phenylpiperidin-4-ol 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1(C2=CC=CC=C2)O)CC3=CC=CC=C3

Technology Process of 1-Benzyl-4-phenylpiperidin-4-ol

There total 19 articles about 1-Benzyl-4-phenylpiperidin-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 3612-20-2
1-phenylmethyl-4-piperidone

: phenylmagnesium bromide

: 63843-83-4
1-benzyl-4-hydroxy-4-phenylpiperidine

Guidance literature:: for 1h; Ambient temperature;
DOI:10.1055/s-1993-25946

Reference yield: 80.0%

: 3612-20-2
1-phenylmethyl-4-piperidone

: 591-51-5
phenyllithium

: 63843-83-4
1-benzyl-4-hydroxy-4-phenylpiperidine

Guidance literature:: In tetrahydrofuran;
DOI:10.1016/0960-894X(96)00419-2

Reference yield: 78.0%

: 108-86-1,52753-63-6
bromobenzene

: 3612-20-2
1-phenylmethyl-4-piperidone

: 63843-83-4
1-benzyl-4-hydroxy-4-phenylpiperidine

Guidance literature:: bromobenzene; With iodine; magnesium; In tetrahydrofuran; Inert atmosphere; Reflux;

1-phenylmethyl-4-piperidone; In tetrahydrofuran; at 20 ℃; for 3h; Inert atmosphere; Cooling with ice;
DOI:10.1016/j.bmcl.2012.01.122