N-(1-Benzyl-4-phenylpiperidin-4-YL)acetamide

Base Information

Chemical Name:N-(1-Benzyl-4-phenylpiperidin-4-YL)acetamide
CAS No.:172733-78-7
Molecular Formula:C20H24N2O
Molecular Weight:308.423
Hs Code.:2933399090
European Community (EC) Number:605-645-7
DSSTox Substance ID:DTXSID20596930
Nikkaji Number:J2.675.846G
Wikidata:Q82492345
Mol file:172733-78-7.mol

Synonyms:172733-78-7;N-(1-BENZYL-4-PHENYLPIPERIDIN-4-YL)ACETAMIDE;4-(ACETYLAMINO)-1-BENZYL-4-PHENYLPIPERIDINE;4-acetamido-1-benzyl-4-phenylpiperidine;SCHEMBL4631243;DTXSID20596930;JZIHXLNGPVLLDT-UHFFFAOYSA-N;AKOS016013531;EN300-191783;N-(1-Benzyl-4-phenyl-4-piperidinyl)acetamide

Suppliers and Price of N-(1-Benzyl-4-phenylpiperidin-4-YL)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-(1-Benzyl-4-phenylpiperidin-4-yl)acetamide 95+%
1g
$ 668.00

Chemenu
N-(1-benzyl-4-phenylpiperidin-4-yl)acetamide 95%
1g
$ 632.00

American Custom Chemicals Corporation
4-(ACETYLAMINO)-1-BENZYL-4-PHENYLPIPERIDINE 95.00%
5MG
$ 496.63

Total 9 raw suppliers

Chemical Property of N-(1-Benzyl-4-phenylpiperidin-4-YL)acetamide

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:491.59oC at 760 mmHg
Flash Point:251.105oC
PSA：35.83000
Density:1.127g/cm3
LogP:4.09220
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:308.188863393
Heavy Atom Count:23
Complexity:375

Purity/Quality:

98% ^*data from raw suppliers

N-(1-Benzyl-4-phenylpiperidin-4-yl)acetamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1(CCN(CC1)CC2=CC=CC=C2)C3=CC=CC=C3

Technology Process of N-(1-Benzyl-4-phenylpiperidin-4-YL)acetamide

There total 8 articles about N-(1-Benzyl-4-phenylpiperidin-4-YL)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 63843-83-4
1-benzyl-4-hydroxy-4-phenylpiperidine

: 64-19-7,77671-22-8
acetic acid

: 172733-78-7
N-(1-benzyl-4-phenylpiperidin-4-yl)acetamide

Guidance literature:: With sulfuric acid; In acetonitrile;
DOI:10.1016/0960-894X(96)00419-2

Reference yield: 71.0%

: 63843-83-4
1-benzyl-4-hydroxy-4-phenylpiperidine

: 75-05-8,26809-02-9
acetonitrile

: 172733-78-7
N-(1-benzyl-4-phenylpiperidin-4-yl)acetamide

Guidance literature:: With sulfuric acid; at 0 - 20 ℃;
DOI:10.1016/j.bmc.2011.07.002

Reference yield: 33.0%

: 108-86-1,52753-63-6
bromobenzene

: 126781-38-2
1-benzyl-4-(trifluoromethylsulfonyloxy)-1,2,5,6-tetrahydropyridine

: 75-05-8,26809-02-9
acetonitrile

: 172733-78-7
N-(1-benzyl-4-phenylpiperidin-4-yl)acetamide

Guidance literature:: bromobenzene; With tert.-butyl lithium; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;

With bromo(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)dimethylgermane; In tetrahydrofuran; at -78 ℃; for 16h; Inert atmosphere;

1-benzyl-4-(trifluoromethylsulfonyloxy)-1,2,5,6-tetrahydropyridine; acetonitrile; Further stages;
DOI:10.1039/b816217b