Benzonitrile, 4-(1-phenyl-1H-inden-1-yl)-

Base Information

• Chemical Name: Benzonitrile, 4-(1-phenyl-1H-inden-1-yl)-
• CAS No.: 52033-62-2
• Molecular Formula: C₂₂H₁₅N
• Molecular Weight: 293.368
• Mol file: 52033-62-2.mol

Synonyms:

Chemical Property of Benzonitrile, 4-(1-phenyl-1H-inden-1-yl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzonitrile, 4-(1-phenyl-1H-inden-1-yl)-

There total 7 articles about Benzonitrile, 4-(1-phenyl-1H-inden-1-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

1-(p-bromophenyl)-1-phenylindene (52033-61-1) → 1-(p-cyanophenyl)-1-phenylindene (52033-62-2)

Guidance literature:

In various solvent(s); for 2h; Heating;

DOI:10.1021/jo00318a018

Reference yield:

(4-bromophenyl)(phenyl)methanone (90-90-4) → 1-(p-cyanophenyl)-1-phenylindene (52033-62-2)

Guidance literature:

Multi-step reaction with 6 steps

1: 56 percent / diethyl ether; benzene

2: 64 percent / Heating; 1.)3 h 150 deg C 2.)30 min 160 deg C

3: 1.) phosphorus pentachloride; 2.) stannic chloride

4: 83 percent / sodium borohydride / aq. ethanol / 54 h / Ambient temperature

5: 81 percent / p-toluenesulfonic acid / acetic acid / 0.67 h / Heating

6: 73 percent / various solvent(s) / 2 h / Heating

With sodium tetrahydroborate; phosphorus pentachloride; tin(IV) chloride; toluene-4-sulfonic acid; In diethyl ether; ethanol; acetic acid; benzene;

DOI:10.1021/jo00318a018

Reference yield:

1-(p-bromophenyl)-1,1-diphenylcarbinol (61623-62-9) → 1-(p-cyanophenyl)-1-phenylindene (52033-62-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 64 percent / Heating; 1.)3 h 150 deg C 2.)30 min 160 deg C

2: 1.) phosphorus pentachloride; 2.) stannic chloride

3: 83 percent / sodium borohydride / aq. ethanol / 54 h / Ambient temperature

4: 81 percent / p-toluenesulfonic acid / acetic acid / 0.67 h / Heating

5: 73 percent / various solvent(s) / 2 h / Heating

With sodium tetrahydroborate; phosphorus pentachloride; tin(IV) chloride; toluene-4-sulfonic acid; In ethanol; acetic acid;

DOI:10.1021/jo00318a018

upstream raw materials:

1-(p-bromophenyl)-1-phenylindene

(4-bromophenyl)(phenyl)methanone

1-(p-bromophenyl)-1,1-diphenylcarbinol

3-(p-bromophenyl)-3,3-diphenylpropionic acid

Downstream raw materials:

2-phenyl-3-(p-cyanophenyl)indene

2-(p-cyanophenyl)-3-phenylindene