3-CHLORO-4-ETHOXYANILINE

Base Information

• Chemical Name: 3-CHLORO-4-ETHOXYANILINE
• CAS No.: 5211-02-9
• Molecular Formula: C8H10ClNO
• Molecular Weight: 171.626
• Hs Code.: 2922290090
• Mol file: 5211-02-9.mol

Synonyms:3-chloro-4-ethoxyaniline;

Chemical Property of 3-CHLORO-4-ETHOXYANILINE

Chemical Property:

• Vapor Pressure: 0.00292mmHg at 25°C
• Boiling Point: 284.8oC at 760 mmHg
• Flash Point: 126oC
• PSA: 35.25000
• Density: 1.19g/cm3
• LogP: 2.90210
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

98%Min ^*data from raw suppliers

3-Chloro-4-ethoxyaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-CHLORO-4-ETHOXYANILINE

There total 4 articles about 3-CHLORO-4-ETHOXYANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.6%

2-(2-chloro-4-nitrophenoxy)ethyl-1-yl (5493-71-0) → 3-Chloro-4-ethoxy-phenylamine (5211-02-9)

Guidance literature:

With iron; ammonium chloride; In ethanol; at 80 ℃; for 3h;

Reference yield:

acetic acid-(4-ethoxy-3-chloro-anilide) (108761-49-5) → 3-Chloro-4-ethoxy-phenylamine (5211-02-9)

Guidance literature:

With hydrogenchloride;

Reference yield:

4-ethoxyacetanilide (62-44-2,105931-34-8) → 3-Chloro-4-ethoxy-phenylamine (5211-02-9)

Guidance literature:

Multi-step reaction with 2 steps

1: glacial acetic acid; hydrochloric acid

2: hydrochloric acid

With hydrogenchloride; acetic acid;

upstream raw materials:

2-(2-chloro-4-nitrophenoxy)ethyl-1-yl

acetic acid-(4-ethoxy-3-chloro-anilide)

4-ethoxyacetanilide

Downstream raw materials:

N-(4-ethoxy-3-chloro-phenyl)-N'-(4-chloro-3-trifluoromethyl-phenyl)-urea

acetic acid-(4-ethoxy-3-chloro-anilide)

N-(4-ethoxy-3-chloro-phenyl)-glycine

Refernces