1-[(2,2-Dichlorocyclopropyl)methyl]-4-methoxybenzene

Base Information

Chemical Name:1-[(2,2-Dichlorocyclopropyl)methyl]-4-methoxybenzene
CAS No.:52178-88-8
Molecular Formula:C11H12Cl2O
Molecular Weight:231.122
Hs Code.:
DSSTox Substance ID:DTXSID80409299
Mol file:52178-88-8.mol

Synonyms:1-[(2,2-dichlorocyclopropyl)methyl]-4-methoxybenzene;52178-88-8;STK061844;DTXSID80409299;AKOS003597246;AKOS022083438;2-(4-methoxybenzyl)-1,1-dichloro-cyclopropane

Suppliers and Price of 1-[(2,2-Dichlorocyclopropyl)methyl]-4-methoxybenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 1-[(2,2-Dichlorocyclopropyl)methyl]-4-methoxybenzene

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:230.0265204
Heavy Atom Count:14
Complexity:198

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CC2CC2(Cl)Cl

Technology Process of 1-[(2,2-Dichlorocyclopropyl)methyl]-4-methoxybenzene

There total 1 articles about 1-[(2,2-Dichlorocyclopropyl)methyl]-4-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 140-67-0
Estragole

: phenyl dichlorobromomethylmercury (C₆ H₅ HgCCl₂ Br)

: 52178-88-8
2-(4-methoxybenzyl)-1,1-dichlorocyclopropane

Guidance literature:: In benzene;

Reference yield: 78.0%

: 1066-45-1
trimethyltin(IV)chloride

: 52178-88-8
2-(4-methoxybenzyl)-1,1-dichlorocyclopropane

: 1,1-bis(trimethylstannyl)-2-(2-methoxybenzyl)cyclopropane

Guidance literature:: With sodium; In ammonia; Irradiation (UV/VIS); NH3 was distd. into flask at -78°C under N2; Me3SnCl (2.2 equiv.)was added; Na was added until no more solid was present; cyclopropane ( 1 equiv.) was added; irradiated for 2 h; quenched with NH4NO3; evapd.; H2O added; extd. (CH2Cl2, Et2O); org. phase dried (MgSO4); filtered; solvent removed; chromd. (silica gel plates, petroleum ether);
DOI:10.1021/om801104e