2,4-Dibromo-6-isopropyl-3-methylphenol

Base Information

• Chemical Name: 2,4-Dibromo-6-isopropyl-3-methylphenol
• CAS No.: 52262-38-1
• Molecular Formula: C10H12Br2O
• Molecular Weight: 308.013
• Mol file: 52262-38-1.mol

Synonyms:Phenol, 2,4-dibromo-3-methyl-6-(1-methylethyl)-;2,4-Dibrom-6-isopropyl-3-methyl-phenol;2.6-Dibrom-3-oxy-1-methyl-4-isopropyl-benzol;4,6-dibromothymol;2,4-Dibromo-6-isopropyl-3-methyl-phenol;2.6-Dibrom-3-oxy-p-cymol;2,4-dibromo-6-isopropyl-3-methylphenol;

Chemical Property of 2,4-Dibromo-6-isopropyl-3-methylphenol

Chemical Property:

• Melting Point: 1.9°C
• Refractive Index: 1.5560 (estimate)
• Boiling Point: 175 °C (25 mmHg)
• PSA: 20.23000
• Density: 1.6094 (rough estimate)
• LogP: 4.34900

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-Dibromo-6-isopropyl-3-methylphenol

There total 18 articles about 2,4-Dibromo-6-isopropyl-3-methylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

thymol (89-83-8) → 2,4-dibromo-6-isopropyl-3-methylphenol (52262-38-1)

Guidance literature:

With ammonium metavanadate; perchloric acid; dihydrogen peroxide; potassium bromide; In water; at 20 ℃; for 24h; pH=1;

DOI:10.3390/molecules25040866

Reference yield: 62.0%

Menthone (10458-14-7,17627-49-5,7786-64-3) → 2,4-dibromo-6-isopropyl-3-methylphenol (52262-38-1)

Guidance literature:

With hydrogen bromide; In dimethyl sulfoxide; at 75 ℃; for 22h;

DOI:10.1023/A:1012737123973

Reference yield:

thymol (89-83-8) → thymoquinone (490-91-5) + 2,4-dibromo-6-isopropyl-3-methylphenol (52262-38-1) + 2-bromo-6-isopropyl-3-methylphenol (13019-31-3) + 4-bromo-2-isopropyl-5-methylphenol (15062-34-7)

Guidance literature:

With perchloric acid; ammonium metavanadate; dihydrogen peroxide; potassium bromide; In water; at 45 ℃; for 24h; pH=1; Catalytic behavior;

DOI:10.1002/ejic.201500086

upstream raw materials:

thymol

thymol sulfonic acid

chloroform

bromine

Downstream raw materials:

4-amino-2-bromo-6-isopropyl-3-methyl-phenol

2-isopropyl-5-methyl-5-(5-methylfuran-2-yl)cyclohex-2-ene-1,4-dione

5-isopropyl-2-methyl-3-(5-methylfuran-2-yl)cyclohexa-2,5-diene-1,4-dione

(5-isopropyl-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)boronic acid

Refernces

• 1、 Piombino, Claudio,Lange, Heiko,Sabuzi, Federica,Galloni, Pierluca,Conte, Valeria,Crestini, Claudia. "Lignosulfonate microcapsules for delivery and controlled release of thymol and derivatives". . . Retrieved 2020/02/25.
• 2、 Maurya, Mannar R.,Jangra, Nancy,Avecilla, Fernando,Correia, Isabel. "4,6-Diacetyl Resorcinol Based Vanadium(V) Complexes: Reactivity and Catalytic Applications". . p. 314 - 329. Retrieved 2019/01/24.