2-Methoxy-5-sulfamoylbenzamide

Base Information

Chemical Name:2-Methoxy-5-sulfamoylbenzamide
CAS No.:52395-25-2
Molecular Formula:C8H10N2O4S
Molecular Weight:230.24100
Hs Code.:
UNII:3ZFR2SNF7B
Wikidata:Q107837651
ChEMBL ID:CHEMBL2139902
Mol file:52395-25-2.mol

Synonyms:2-methoxy-5-sulfamoylbenzamide;52395-25-2;5-(aminosulfonyl)-2-methoxybenzamide;5-aminosulfonyl-2-methoxybenzamide;3ZFR2SNF7B;MLS000704379;2-Methoxy-5-sulphamoylbenzamide;Benzamide, 5-(aminosulfonyl)-2-methoxy-;SMR000230492;Sulpiride Imp. E (EP);Sulpiride Impurity E;Sulpride Impurity E;Opera_ID_1668;UNII-3ZFR2SNF7B;Sulpiride impurity E [EP];Oprea1_871656;CHEMBL2139902;SCHEMBL11408239;HMS2611C04;AKOS008937553;SULPIRIDE IMPURITY E [EP IMPURITY];FT-0672203;EN300-270522;AE-641/30110001;Z33545916

Suppliers and Price of 2-Methoxy-5-sulfamoylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Methoxy-5-sulfamoylbenzamide
1g
$ 1455.00

American Custom Chemicals Corporation
2-METHOXY-5-SULFAMOYLBENZAMIDE 95.00%
5MG
$ 500.67

Total 10 raw suppliers

Chemical Property of 2-Methoxy-5-sulfamoylbenzamide

Chemical Property:

Melting Point:245-246℃ (ethanol water )
Boiling Point:437.3±55.0 °C(Predicted)
PKA:9.99±0.60(Predicted)
PSA：121.85000
Density:1.429±0.06 g/cm3(Predicted)
LogP:2.10680
Storage Temp.:Refrigerator, under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:-0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:230.03612798
Heavy Atom Count:15
Complexity:335

Purity/Quality:

97% ^*data from raw suppliers

2-Methoxy-5-sulfamoylbenzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)S(=O)(=O)N)C(=O)N
Uses 2-Methoxy-5-sulfamoylbenzamide is a metabolite of the antipsychotic drug, Sulpiride (S689145).

Technology Process of 2-Methoxy-5-sulfamoylbenzamide

There total 1 articles about 2-Methoxy-5-sulfamoylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 606-45-1
2-methoxybenzoic acid methyl ester

: 52395-25-2
5-(aminosulfonyl)-2-methoxybenzamide

Guidance literature:: With chlorosulfonic acid; ammonium hydroxide; Yield given. Multistep reaction; 1.) chloroform, 30 min at 20 deg C, then 2 h at 35-40 deg C; 2.) 20-25 deg C;