Benzenepropanoic acid, a-[(phenylamino)carbonyl]-

Base Information

• Chemical Name: Benzenepropanoic acid, a-[(phenylamino)carbonyl]-
• CAS No.: 5243-31-2
• Molecular Formula: C16H15NO3
• Molecular Weight: 269.3
• Mol file: 5243-31-2.mol

Synonyms:

Chemical Property of Benzenepropanoic acid, a-[(phenylamino)carbonyl]-

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenepropanoic acid, a-[(phenylamino)carbonyl]-

There total 17 articles about Benzenepropanoic acid, a-[(phenylamino)carbonyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-benzylidene-2-phenylisoxazolidine-3,5-dione (5289-18-9) → An-mPhe-OH (5243-31-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran;

DOI:10.1002/hlca.19650480817

Reference yield:

benzaldehyde (100-52-7) → An-mPhe-OH (5243-31-2)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol

2: H₂ / Pd-C / tetrahydrofuran

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol;

DOI:10.1002/hlca.19650480817

Reference yield:

N-Phenylhydroxylamine (100-65-2) → An-mPhe-OH (5243-31-2)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) (alkaline hydrolysis), (ii) SOCl₂, (iii) /BRN= 774687/, CH₂Cl₂

2: ethanol

3: H₂ / Pd-C / tetrahydrofuran

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol;

DOI:10.1002/hlca.19650480817

upstream raw materials:

aniline

diethyl 2-benzylmalonate

5-benzyl-6-chloro-3-phenyl-[1,3]oxazine-2,4-dione

4-benzylidene-2-phenylisoxazolidine-3,5-dione

Downstream raw materials:

carbonic-acid

hydrocinnamanilide

Refernces