1-Methoxy-2-cyanonaphthalene

Base Information

Chemical Name:1-Methoxy-2-cyanonaphthalene
CAS No.:52449-79-3
Molecular Formula:C12H9NO
Molecular Weight:183.20600
Hs Code.:
DSSTox Substance ID:DTXSID10484579
Wikidata:Q82323072
Mol file:52449-79-3.mol

Synonyms:52449-79-3;1-methoxynaphthalene-2-carbonitrile;1-Methoxy-2-naphthonitrile;1-Methoxy-2-cyanonaphthalene;SCHEMBL24476762;DTXSID10484579;FT-0764273

Suppliers and Price of 1-Methoxy-2-cyanonaphthalene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
2-Cyano-1-methoxynaphthalene
1g
$ 1634.45

Alichem
2-Cyano-1-methoxynaphthalene
500mg
$ 1058.40

Alichem
2-Cyano-1-methoxynaphthalene
250mg
$ 680.00

Total 5 raw suppliers

Chemical Property of 1-Methoxy-2-cyanonaphthalene

Chemical Property:

Melting Point:50-51 °C(Solv: methanol (67-56-1))
Boiling Point:362.8±15.0 °C(Predicted)
PSA：33.02000
Density:1.16±0.1 g/cm3(Predicted)
LogP:2.72008
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:183.068413911
Heavy Atom Count:14
Complexity:242

Purity/Quality:

97% ^*data from raw suppliers

2-Cyano-1-methoxynaphthalene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC2=CC=CC=C21)C#N

Technology Process of 1-Methoxy-2-cyanonaphthalene

There total 10 articles about 1-Methoxy-2-cyanonaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 931-97-5
1-hydroxy-1-cyclohexanecarbonitrile

: 883-21-6
1-methoxy-2-naphthoic acid

: 52449-79-3
1-methoxy-[2]naphthonitrile

Guidance literature:: With bis(trifluoromethyl sulfate)palladium; silver carbonate; In dimethyl sulfoxide; N,N-dimethyl-formamide; at 100 ℃;
DOI:10.1055/s-0030-1258526

Reference yield:

: 5807-02-3
4-morpholinoacetonitrile

: C₁₈H₁₄O₃

: 52449-79-3
1-methoxy-[2]naphthonitrile

Guidance literature:: With 3,4-thiene-2,3-diylbis(dicyclohexylphosphine); nickel(II) acetate tetrahydrate; sodium phosphate; In 1,4-dioxane; at 150 - 160 ℃; for 12h; Inert atmosphere;
DOI:10.1055/s-0040-1705943

Reference yield:

: 3262-04-2
1-chloro-3,4-dihydronaphthalene-2-carbaldehyde oxime

: 52449-79-3
1-methoxy-[2]naphthonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: Py / acetic anhydride

2: aq. H₃PO₄, NO4>

3: methanol

With pyridine; nitrosylsulfuric acid; phosphoric acid; In methanol; acetic anhydride;