(1S)-2,6,6-Trimethyl-2-cyclohexene-1-methanol

Base Information

Chemical Name:(1S)-2,6,6-Trimethyl-2-cyclohexene-1-methanol
CAS No.:52646-93-2
Molecular Formula:C10H18O
Molecular Weight:154.252
Hs Code.:
DSSTox Substance ID:DTXSID701252469
Nikkaji Number:J2.770.256B
Mol file:52646-93-2.mol

Synonyms:(1S)-2,6,6-Trimethyl-2-cyclohexene-1-methanol;SCHEMBL9410639;DTXSID701252469;52646-93-2

Suppliers and Price of (1S)-2,6,6-Trimethyl-2-cyclohexene-1-methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1S)-2,6,6-Trimethyl-2-cyclohexene-1-methanol

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:154.135765193
Heavy Atom Count:11
Complexity:168

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CCCC(C1CO)(C)C
Isomeric SMILES:CC1=CCCC([C@@H]1CO)(C)C

Technology Process of (1S)-2,6,6-Trimethyl-2-cyclohexene-1-methanol

There total 20 articles about (1S)-2,6,6-Trimethyl-2-cyclohexene-1-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 52567-43-8
(S)-Methyl-α-cyclogeraniumsaeure

: 52646-93-2
[(S)-2,6,6-trimethylcyclohex-2-enyl]methanol

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; at -10 ℃; for 1h;
DOI:10.1016/S0957-4166(00)00007-0

Reference yield: 36.0%

: 108-05-4,9003-20-7
vinyl acetate

: 6627-74-3
(+/-)-α-cyclogeraniol

: 192724-31-5
(R)-(2,6,6-trimethylcyclohex-2-en-1-yl)methyl acetate

: 52646-93-2
[(S)-2,6,6-trimethylcyclohex-2-enyl]methanol

Guidance literature:: With Lipase PS; triethylamine; In hexane; at 0 ℃; for 120h; Molecular sieve; Enzymatic reaction;
DOI:10.1021/ol102296t

Reference yield:

: 4698-08-2
(E)-geranic acid

: 52646-93-2
[(S)-2,6,6-trimethylcyclohex-2-enyl]methanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: H₃PO₄ / toluene / 2 h / 100 °C

1.2: (-)-α-methylbenzylamine

2.1: 90 percent / K₂CO₃ / acetone / 3 h / 20 °C

3.1: 90 percent / LiAlH₄ / diethyl ether / 1 h / -10 °C

With lithium aluminium tetrahydride; phosphoric acid; potassium carbonate; In diethyl ether; acetone; toluene; 1.1: Cyclization / 1.2: racemate resolution / 2.1: Methylation / 3.1: Reduction;