1H-Isoindole-1,3(2H)-dione, 2-[(2-benzoylphenyl)methyl]-

Base Information

Chemical Name:1H-Isoindole-1,3(2H)-dione, 2-[(2-benzoylphenyl)methyl]-
CAS No.:52839-46-0
Molecular Formula:C22H15NO3
Molecular Weight:341.366
Hs Code.:
DSSTox Substance ID:DTXSID60462822
Nikkaji Number:J1.670.484I
Wikidata:Q82287426
Mol file:52839-46-0.mol

Synonyms:52839-46-0;1H-Isoindole-1,3(2H)-dione, 2-[(2-benzoylphenyl)methyl]-;DTXSID60462822

Suppliers and Price of 1H-Isoindole-1,3(2H)-dione, 2-[(2-benzoylphenyl)methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Isoindole-1,3(2H)-dione, 2-[(2-benzoylphenyl)methyl]-

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:341.10519334
Heavy Atom Count:26
Complexity:542

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C2=CC=CC=C2CN3C(=O)C4=CC=CC=C4C3=O

Technology Process of 1H-Isoindole-1,3(2H)-dione, 2-[(2-benzoylphenyl)methyl]-

There total 3 articles about 1H-Isoindole-1,3(2H)-dione, 2-[(2-benzoylphenyl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 136918-14-4,85-41-6
phthalimide

: 59310-31-5
2-bromomethylbenzophenone

: 52839-46-0
2-(2-benzoylbenzyl)isoindoline-1,3-dione

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; for 20h;
DOI:10.1107/S0108270101003870

Reference yield: 57.0%

: 591-50-4
iodobenzene

: 67-66-3,8013-54-5
chloroform

: 380430-66-0
2-(N-phthalimidomethyl)-benzeneboronic acid pinacol ester

: 52839-46-0
2-(2-benzoylbenzyl)isoindoline-1,3-dione

Guidance literature:: With dmap; palladium diacetate; potassium hydroxide; In chloroform; toluene; at 80 ℃; for 12h;
DOI:10.1021/acs.joc.6b02711

Reference yield:

: 131-58-8
2-Methylbenzophenone

: 52839-46-0
2-(2-benzoylbenzyl)isoindoline-1,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 2.7 g / N-bromosuccinimide; AIBN / CCl₄ / 48 h / 50 °C

2: 2.62 g / potassium carbonate / dimethylformamide

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); potassium carbonate; In tetrachloromethane; N,N-dimethyl-formamide;
DOI:10.3987/com-01-s(k)5