4-Anilino-6,6-dimethyl-5,6-dihydropyridine-2(1H)-thione

Base Information

Chemical Name:4-Anilino-6,6-dimethyl-5,6-dihydropyridine-2(1H)-thione
CAS No.:58913-46-5
Molecular Formula:C13H16N2S
Molecular Weight:232.349
Hs Code.:
NSC Number:351158
DSSTox Substance ID:DTXSID00393828

Synonyms:58913-46-5;NSC351158;DTXSID00393828;NSC-351158;4-Anilino-6,6-dimethyl-5,6-dihydropyridine-2(1H)-thione;6,6-dimethyl-4-(phenylamino)-5,6-dihydropyridine-2(1h)-thione

Suppliers and Price of 4-Anilino-6,6-dimethyl-5,6-dihydropyridine-2(1H)-thione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 4-Anilino-6,6-dimethyl-5,6-dihydropyridine-2(1H)-thione

Chemical Property:

Vapor Pressure:0.000122mmHg at 25°C
Boiling Point:335.1°Cat760mmHg
Flash Point:156.5°C
Density:1.15g/cm³
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:232.10341969
Heavy Atom Count:16
Complexity:301

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC(=CC(=S)N1)NC2=CC=CC=C2)C

Technology Process of 4-Anilino-6,6-dimethyl-5,6-dihydropyridine-2(1H)-thione

There total 12 articles about 4-Anilino-6,6-dimethyl-5,6-dihydropyridine-2(1H)-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.0%

: 16325-43-2
1-phenyl-4,4,6-trimethyl-1,4-dihydropyrimidine-2(3H)thione

: 58913-46-5
6,6-dimethyl-4-(phenylamino)-5,6-dihydropyridine-2(1H)-thione

: 103-85-5
monophenylthiourea

Guidance literature:: at 140 - 160 ℃; for 3.5h;

Reference yield:

: 62-53-3
aniline

: 6,6-dimethyl-2-thioxo-4-piperidone

: 58913-46-5
6,6-dimethyl-4-(phenylamino)-5,6-dihydropyridine-2(1H)-thione

Guidance literature:: With acetic acid; In benzene; for 4h; Reflux;
DOI:10.1007/s00706-015-1503-y

Reference yield:

: 59743-23-6
4-(dimethylamino)-5,6-dihydro-6,6-dimethyl-2(1H)-pyridinthione

: 58913-46-5
6,6-dimethyl-4-(phenylamino)-5,6-dihydropyridine-2(1H)-thione

Guidance literature:: Multi-step reaction with 2 steps

1: 2.7 g / 1N KOH/H₂O / 16 h / Heating

2: 1.8 g / 3 h / Heating

With potassium hydroxide; water;
DOI:10.1007/BF00911085