3-(4-acetamidophenyl)propanoic acid

Base Information

• Chemical Name: 3-(4-acetamidophenyl)propanoic acid
• CAS No.: 6325-43-5
• Molecular Formula: C11H13 N O3
• Molecular Weight: 207.23
• Hs Code.: 2924299090
• Mol file: 6325-43-5.mol

Synonyms:Hydrocinnamicacid, p-acetamido- (6CI,7CI,8CI); 3-(4-Acetylaminophenyl)propanoic acid;3-(4-Acetylaminophenyl)propionic acid; 3-(p-Acetylaminophenyl)propionic acid;4-(Acetylamino)benzenepropanoic acid; NSC 30906; p-Acetamidohydrocinnamic acid

Chemical Property of 3-(4-acetamidophenyl)propanoic acid

Chemical Property:

• Vapor Pressure: 5.86E-09mmHg at 25°C
• Boiling Point: 452°C at 760 mmHg
• Flash Point: 227.2°C
• PSA: 66.40000
• Density: 1.244g/cm³
• LogP: 1.73520

Purity/Quality:

99% ^*data from raw suppliers

3-[4-(ACETYLAMINO)PHENYL]PROPANOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(4-acetamidophenyl)propanoic acid

There total 6 articles about 3-(4-acetamidophenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-3-(4-acetylaminophenyl)acrylic acid (67249-02-9) → 3-(4-acetamidophenyl)propanoic acid (6325-43-5)

Guidance literature:

With sodium amalgam;

DOI:10.1039/jr9300000968

Reference yield:

3-(4-aminophenyl)propionic acid (2393-17-1) + acetic anhydride (108-24-7) → 3-(4-acetamidophenyl)propanoic acid (6325-43-5)

Guidance literature:

Reference yield:

carbon dioxide (124-38-9,18923-20-1) + 2-bromo-1-[4-(acetylamino)phenyl]-ethane (39232-06-9) → 3-(4-acetamidophenyl)propanoic acid (6325-43-5) + 2-(4-acetamidophenyl)propanoic acid (99701-07-2)

Guidance literature:

With neocuproine; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; potassium carbonate; In N,N-dimethyl-formamide; at 25 ℃; under 750.075 Torr; Overall yield = 65 %; Overall yield = 27 mg; Irradiation;

DOI:10.1002/chem.201902095

upstream raw materials:

(E)-3-(4-acetylaminophenyl)acrylic acid

3-(4-aminophenyl)propionic acid

acetic anhydride

3-(4-nitrophenyl)propionic acid

Downstream raw materials:

3-(4-amino-3-bromo-phenyl)-propionic acid

3-(4-acetylamino-3-nitro-phenyl)-propionic acid

N-[4-(2-aminoethyl)phenyl]acetamide

Refernces

• 1、 -. "INDANYLAMINO URACILS AND THEIR USE AS ANTIOXIDANTS AND NEUROPROTECTANTS". Page/Page column 51. . Retrieved 2008/06/13.